Xu QQ, Xing WW, Chen G, Dang YW, Luo YG, Chen P, Liang SW, Chen JB. Primitive neuroectodermal tumors of the abdominal wall and vulva in children: Report of two cases and review of the literature. World J Clin Cases 2019; 7(21): 3671-3682 [PMID: 31750352 DOI: 10.12998/wjcc.v7.i21.3671]
Corresponding Author of This Article
Jia-Bo Chen, MD, Doctor, Department of Pediatric Surgery, the First Affiliated Hospital of Guangxi Medical University, No. 6, Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. cjb1205@163.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Case Report
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Xu QQ, Xing WW, Chen G, Dang YW, Luo YG, Chen P, Liang SW, Chen JB. Primitive neuroectodermal tumors of the abdominal wall and vulva in children: Report of two cases and review of the literature. World J Clin Cases 2019; 7(21): 3671-3682 [PMID: 31750352 DOI: 10.12998/wjcc.v7.i21.3671]
Qiong-Qian Xu, Yi-Ge Luo, Peng Chen, Song-Wu Liang, Jia-Bo Chen, Department of Pediatric Surgery, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Wen-Wen Xing, Gang Chen, Yi-Wu Dang, Department of Pathology, the First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Chen G, Dang YW, Luo YG, and Chen JB designed the research, supervised all experiments and corrected the manuscript; Xu QQ, Xing WW , Chen P, and Liang SW collected the clinical information, summarized literature, and performed histologic examination and immunohistochemistry; and Xu QQ wrote first version of the paper.
Supported bythe Guangxi Natural Science Foundation Project, No. 2014GXNSFAA118202.
Informed consent statement: The patients provided informed consent for publication of the case.
Conflict-of-interest statement: The authors of this manuscript have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The manuscript was revised according to the CARE checklist.
Corresponding author: Jia-Bo Chen, MD, Doctor, Department of Pediatric Surgery, the First Affiliated Hospital of Guangxi Medical University, No. 6, Shuangyong Road, Nanning 530021, Guangxi Zhuang Autonomous Region, China. cjb1205@163.com
Telephone: +86-0771-5337362
Received: June 29, 2019 Peer-review started: July 1, 2019 First decision: July 31, 2019 Revised: August 25, 2019 Accepted: September 13, 2019 Article in press: September 12, 2019 Published online: November 6, 2019 Processing time: 132 Days and 22 Hours
Core Tip
Core tip: Primitive neuroectodermal tumors (PNETs) are rare undifferentiated tumors with similar biological characteristics. They belong to the Ewing sarcoma family, accounting for 4% to 17% of all pediatric soft tissue tumors. PNETs usually occur in children and young adults under 25 years of age. We retrospectively analyzed two PNET cases at the First Affiliated Hospital of Guangxi Medical University from May 2012 to June 2014. Both patients were female with an age of onset at 66 and 40 mo. Both patients were provided inpatient visits, outpatient medical records, and telephone follow-ups for more than one year. In this report, we describe in detail the clinical manifestations, treatment protocols, pathological findings, and patient prognoses. This report provides an in-depth analysis of two cases of PNET at rare sites.
