©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 6, 2019; 7(19): 3069-3073
Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3069
Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3069
Hemophagocytic lymphohistiocytosis complicated by polyserositis: A case report
Ping Zhu, Qing Ye, Ting-Hong Li, Tao Han, Feng-Mei Wang, Department of Hepatology and Gastroenterology, Tianjin Third Central Hospital, The Third Central Clinical College of Tianjin Medical University, Tianjin 300170, China
Author contributions: Wang FM designed the report; Li TH and Ye Q collected the patient’s clinical data; Zhu P and Han T analyzed the data and wrote the paper.
Informed consent statement: Consent was obtained from relatives of the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: No conflict of interest exits.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Feng-Mei Wang, MD, Chief Doctor, Department of Hepatology and Gastroenterology, Tianjin Third Central Hospital, The Third Central Clinical College of Tianjin Medical University, 83 Jintang Road, Hedong District, Tianjin 300170, China. wangfengmeitj@126.com
Telephone: +86-22-84112122 Fax: +86-22-24315132
Received: June 27, 2019
Peer-review started: June 29, 2019
First decision: July 31, 2019
Revised: August 28, 2019
Accepted: September 9, 2019
Article in press: September 9, 2019
Published online: October 6, 2019
Processing time: 95 Days and 10 Hours
Peer-review started: June 29, 2019
First decision: July 31, 2019
Revised: August 28, 2019
Accepted: September 9, 2019
Article in press: September 9, 2019
Published online: October 6, 2019
Processing time: 95 Days and 10 Hours
Core Tip
Core tip: Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder of the mononuclear phagocytic system, characterized by systemic proliferation of non-neoplastic histiocytes. HLH, whether primary or secondary, is characterized by activated macrophages in hematopoietic organs, hepatosplenomegaly, cytopenia, and fever, but complicated with polyserositis (PS) is rare. We present a case of HLH in a 46-year-old Chinese woman complicated by pericardial, pleural, and abdomen effusions. It could be important to focus attention on PS in order to broaden our outlook and expand our train of thought.