©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2019; 7(15): 2081-2086
Published online Aug 6, 2019. doi: 10.12998/wjcc.v7.i15.2081
Published online Aug 6, 2019. doi: 10.12998/wjcc.v7.i15.2081
Oncogenic osteomalacia caused by a phosphaturic mesenchymal tumor of the femur: A case report
Dong Tang, Department of Medical Imaging (Radiology), The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China
Xiao-Man Wang, Department of Ultrasound, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China
Yong-Sheng Zhang, Department of Radiology, Hangzhou Hospital of Traditional Medicine, Hangzhou 310015, Zhejiang Province, China
Yong-Sheng Zhang, Department of Radiology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310015, Zhejiang Province, China
Xiao-Xiao Mi, Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou 310015, Zhejiang Province, China
Author contributions: All authors contributed significantly to this case report; Mi XX and Tang D conceived and designed the case report with great input from Wang XM and Zhang YS; Tang D and Wang XM provided the radiological imaging and pathological analyses; Zhang YS was involved in the biomedical analysis; Mi XX wrote the manuscript with input from Wang XM, Zhang YS, and Tang D.
Informed consent statement: Informed written consent was obtained from the patient for publication of this case report and accompanying images.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Xiao-Xiao Mi, PhD, Chief Technician, Institute of Translational Medicine, The Affiliated Hospital of Hangzhou Normal University, 126 Wenzhou Road, Hangzhou 310015, Zhejiang Province, China. mixiaoxiao1987@163.com
Telephone: +86-571-88303635
Supported by Research Fund of Hangzhou Normal University Affiliated Hospital .
Received: February 2, 2019
Peer-review started: February 11, 2019
First decision: May 31, 2019
Revised: June 4, 2019
Accepted: June 20, 2019
Article in press: June 21, 2019
Published online: August 6, 2019
Processing time: 185 Days and 19.9 Hours
Peer-review started: February 11, 2019
First decision: May 31, 2019
Revised: June 4, 2019
Accepted: June 20, 2019
Article in press: June 21, 2019
Published online: August 6, 2019
Processing time: 185 Days and 19.9 Hours
Core Tip
Core tip: Oncogenic osteomalacia caused by phosphaturic mesenchymal tumors is not easily identifiable or detectable due to its rarity and nonspecific presentations. Herein, we provide a successful example of diagnosis of phopshaturic mesenchymal tumor-induced oncogenic osteomalacia in a female patient who presented progressive bone pain. Our case emphasizes that histologically benign phosphaturic mesenchymal tumors that are responsible for oncogenic osteomalacia can also cause bone destruction.