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Case Report
©The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2018; 6(13): 688-693
Published online Nov 6, 2018. doi: 10.12998/wjcc.v6.i13.688
Systemic lupus erythematosus complicated by noncirrhotic portal hypertension: A case report and review of literature
Qi-Bin Yang, Yong-Long He, Chun-Mei Peng, Yu-Feng Qing, Qi He, Jing-Guo Zhou
Qi-Bin Yang, Yong-Long He, Chun-Mei Peng, Yu-Feng Qing, Qi He, Department of Rheumatology and Immunology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Yong-Long He, Clinical Medical School, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, Sichuan Province, China
Jing-Guo Zhou, Department of Rheumatology and Immunology, The First Affiliated Hospital of Chengdu Medical College, Chengdu 610000, Sichuan Province, China
Author contributions: Yang QB, He YL, Peng CM, Qing YF, He Q and Zhou JG contributed to the manuscript writing and revision.
Supported by the National Natural Science Foundation of China, No. 81670801; Medical Association of Sichuan Province, No. S16027; Health and Family Planning Commission of Sichuan Province, No. 17PJ059; and Science and Technology Department of Sichuan Province, No. 2018JY0498.
Informed consent statement: Written informed consent was obtained from the patient.
Conflict-of-interest statement: The authors declare no conflict of interest.
Correspondence to: Jing-Guo Zhou, MD, Professor, Department of Rheumatology and Immunology, The First Affiliated Hospital of Chengdu Medical College, Xindu District, Chengdu 610000, Sichuan Province, China. jgzhou@cmc.edu.cn
Telephone: +86-139-9088-0518
Received: July 11, 2018
Peer-review started: July 11, 2018
First decision: August 3, 2018
Revised: August 7, 2018
Accepted: October 9, 2018
Article in press: October 9, 2018
Published online: November 6, 2018
Processing time: 118 Days and 7 Hours
Core Tip

Core tip: It is rare when systemic lupus erythematosus (SLE) complicated by noncirrhotic portal hypertension (NCPH) is reported, likely because it is under-recognized clinically as well as pathologically. NCPH should be considered in any patient with SLE who suffers from clinical manifestations of portal hypertension in the absence of cirrhosis evidence. Magnetic resonance imaging could be one of several non-invasive detection methods used to rule out cirrhosis. The recognition of clinical presentation and associated risk factors of NCPH contributes to the reduction of its missed and delayed clinical diagnoses.