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World J Clin Cases. Jan 16, 2014; 2(1): 12-15
Published online Jan 16, 2014. doi: 10.12998/wjcc.v2.i1.12
Published online Jan 16, 2014. doi: 10.12998/wjcc.v2.i1.12
Epilepsy triggered by mefloquine in an adult traveler to Uganda
Federico Gobbi, Andrea Rossanese, Dora Buonfrate, Andrea Angheben, Zeno Bisoffi, Department of Tropical Diseases, Sacro Cuore-Don Calabria Hospital, 37024 Verona, Italy
Chiara Postiglione, Prevention Department, ULSS 20 Verona, 37122 Verona, Italy
Author contributions: Gobbi F wrote the manuscript; Rossanese A and Postiglione C managed the patient; Buonfrate D and Angheben A performed the literature search; Bisoffi Z revised the manuscript; all authors have read and approved the final version to be published.
Correspondence to: Federico Gobbi, MD, PhD, Department of Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Via Don A Sempreboni 5, Negrar, 37024 Verona, Italy. federico.gobbi@sacrocuore.it
Telephone: +39-45-6013563 Fax: +39-45-6013694
Received: September 25, 2013
Revised: November 7, 2013
Accepted: December 12, 2013
Published online: January 16, 2014
Processing time: 112 Days and 19.9 Hours
Revised: November 7, 2013
Accepted: December 12, 2013
Published online: January 16, 2014
Processing time: 112 Days and 19.9 Hours
Core Tip
Core tip: We report a case of epilepsy due to mefloquine chemoprophylaxis. Considering that mefloquine is associated with a higher risk of neurologic and psychiatric adverse events than the alternative regimens, we suggest considering mefloquine as a second line choice after atovaquone/proguanil and doxycycline for short-term travelers.