Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Cases. Oct 26, 2026; 14(28): 125577
Published online Oct 26, 2026. doi: 10.12998/wjcc.125577
Published online Oct 26, 2026. doi: 10.12998/wjcc.125577
Peripheral giant cell granuloma associated with dental prostheses: A case report
Abdulmajeed A Aljabr, Department of Preventive Dental Sciences, College of Dentistry, Majmaah University, Al-Majmaah 11952, Saudi Arabia
Khalid S Dobaian, Imam Abdulrahman Bin Faisal University, College of Dentistry, Dammam 31441, Saudi Arabia
Author contributions: Aljabr AA contributed to methodology, project administration, resources, visualization, writing - original draft; Dobaian KS contributed to validation, supervision; Aljabr AA and Dobaian KS contributed to conceptualization, investigation, writing - review & editing.
AI contribution statement: The authors take full responsibility and accountability for all content of this manuscript, including any portions for which AI tools were used as assistive technologies. All AI-assisted outputs were carefully reviewed, validated, and approved by the authors. AI tools were not used to generate original scientific data, perform independent scientific analyses, or draw scientific conclusions.
Informed consent statement: Written informed consent was obtained from the patient for publication of the case details and accompanying clinical images.
Conflict-of-interest statement: All authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Abdulmajeed A Aljabr, Academic Fellow, Assistant Professor, Depart
Received: July 15, 2026
Revised: August 7, 2026
Accepted: October 21, 2026
Published online: October 26, 2026
Processing time: 105 Days and 4.2 Hours
Revised: August 7, 2026
Accepted: October 21, 2026
Published online: October 26, 2026
Processing time: 105 Days and 4.2 Hours
Core Tip
Core Tip: Peripheral giant cell granuloma is a relatively common reactive lesion of the oral cavity that arises exclusively on the gingiva or edentulous alveolar ridge. It is generally regarded as a non-neoplastic proliferation associated with chronic local irritation or trauma, likely originating from the periodontal ligament or periosteum. The report highlights the need for clinicopathologic correlation, cautious causal wording, elimination of local irritants, appropriate prosthodontic redesign when indicated, and follow-up to reduce recurrence.