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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Cases. Aug 16, 2026; 14(23): 121781
Published online Aug 16, 2026. doi: 10.12998/wjcc.121781
Management of catatonia in Parkinson’s disease with comorbid bipolar disorder: A case report and review of literature
Himaly Bansal, Nikhil Kamal, Subho Chakrabarti
Himaly Bansal, Nikhil Kamal, Subho Chakrabarti, Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Author contributions: Bansal H, Kamal N, and Chakrabarti S were involved in the management of this patient, conducted the literature review and prepared the first draft of the manuscript, and prepared the revised version of the manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
AI contribution statement: No AI tools have been used to prepare this manuscript.
Informed consent statement: The patient has given written informed consent for the details of his illness to be submitted for publication. This has been included. The case report does not include any identifying details of the patient.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Subho Chakrabarti, MD, FRCPsych, Professor, Department of Psychiatry, Postgraduate Institute of Medical Education and Research, 12 Sector, Chandigarh 160012, India. subhochd@yahoo.com
Received: April 1, 2026
Revised: May 24, 2026
Accepted: June 25, 2026
Published online: August 16, 2026
Processing time: 133 Days and 10.6 Hours
Core Tip

Core Tip: Bipolar disorder (BD) is an infrequently reported but disabling non-motor manifestation of Parkinson’s disease (PD). The presentation of a 68-year-old man with comorbid BD and PD illustrates the comorbidity’s typical features, such as BD occurring in the pre-motor phase of PD, its association with anxiety, apathy, and other non-motor symptoms, and its poor prognosis. Catatonia is an uncommon manifestation of treatment-resistant depressive episodes in comorbid BD and PD. When benzodiazepines for catatonia fail, clinicians should actively consider electroconvulsive therapy. Close collaboration between psychiatrists and neurologists is essential for early detection and proper management of coexisting BD and PD with catatonia.

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