Decoding the glycemic paradox: The imperative for frailty-centered inpatient diabetes care

doi:10.12998/wjcc.123085

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 14, Issue 21

This Article

(4)

(0)

(3)

(22)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Clinical Cases

ISSN

2307-8960

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Editorial

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Cases. Jul 26, 2026; 14(21): 123085
Published online Jul 26, 2026. doi: 10.12998/wjcc.123085

Decoding the glycemic paradox: The imperative for frailty-centered inpatient diabetes care

Basavraj S Nagoba, Sachin S Bhavthankar, Ajay M Gavkare

Basavraj S Nagoba, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Latur 413531, Maharashtra, India

Sachin S Bhavthankar, Department of Biochemistry, Maharashtra Institute of Medical Sciences and Research, Latur 413512, India

Ajay M Gavkare, Department of Physiology, Government Medical College, Buldhana 443001, Maharashtra, India

Author contributions: Nagoba BS designed the overall concept and outline of the manuscript; Bhavthankar SS and Gavkare AM contributed to the discussion and design of the manuscript; Nagoba BS, Bhavthankar SS, and Gavkare AM contributed to the writing, editing the manuscript, and review of literature; all authors contributed to finalising the manuscript.

AI contribution statement: We have used Gemini as an AI tool for grammatical and typographical corrections only.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Basavraj S Nagoba, Professor, Department of Microbiology, Maharashtra Institute of Medical Sciences and Research (Medical College), Vishwanathpuram, Ambajogai Road, Latur 413531, Maharashtra, India. basavraj.nagoba@mimsr.edu.in

Received: May 8, 2026
Revised: June 8, 2026
Accepted: July 1, 2026
Published online: July 26, 2026
Processing time: 75 Days and 2 Hours

Core Tip

Core Tip: In frail older adults with type 2 diabetes, lower glycated haemoglobin levels may paradoxically be associated with increased mortality, reflecting overtreatment, hypoglycemia, and underlying physiological decline. Frailty is a key modifier of risk and should guide glycemic targets, particularly in the inpatient setting. Routine frailty assessment, individualized treatment goals, and deprescribing of high-risk therapies are essential. A shift from rigid glycemic control to a safety-focused, patient-centered approach is crucial to improve outcomes in this vulnerable population.