Perinatal asphyxia and left ventricular mass: Redefining cardiac assessment

doi:10.12998/wjcc.120254

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Clin Cases. Jul 16, 2026; 14(20): 120254
Published online Jul 16, 2026. doi: 10.12998/wjcc.120254

Perinatal asphyxia and left ventricular mass: Redefining cardiac assessment

Regi Varghese John, Anupama Subash, Arkiath Veettil Raveendran

Regi Varghese John, Specialist in Internal Medicine, Badr Al Samaa Hospital, Barka 320, Al Batinah South, Oman

Anupama Subash, University of Windsor, Windsor, Ontario N9B 3P4, Canada

Arkiath Veettil Raveendran, Department of Internal Medicine, Government Medical College, Kozhikode 673010, Kerala, India

Author contributions: John RV, Subash A, and Raveendran AV, collected the data, and wrote and revised the manuscript; Raveendran AV designed the manuscript. All the author read and approved the final version of the manuscript to be published.

AI contribution statement: Free versions of ChatGPT, Grammarly, DeepL, Claude and Jenni AI were only used for grammar revision, language and table polishing in manuscript preparation. No manuscript text, research design, data analysis, result interpretation or figures were AI-generated; all research ideas, data and conclusions are original to the authors. All AI-processed content was fully checked and validated by authors, who bear complete responsibility for the manuscript’s originality, accuracy and integrity.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Corresponding author: Arkiath Veettil Raveendran, MD, Chief Physician, FRCP, Department of Internal Medicine, Government Medical College, Medical College Junction, Mavoor Road, Kozhikode 673010, Kerala, India. raveendranav@yahoo.co.in

Received: February 24, 2026
Revised: June 3, 2026
Accepted: June 24, 2026
Published online: July 16, 2026
Processing time: 138 Days and 13.1 Hours

Core Tip

Core Tip: Structural cardiac assessment, particularly left ventricular mass estimation, provides complementary information to functional echocardiographic parameters and biochemical markers of myocardial injury, in neonates with perinatal asphyxia and may enhance early risk stratification, guide hemodynamic management, and improve long-term cardiovascular surveillance. Left ventricular mass correlates with gestational age, birth weight, and asphyxia severity and provide a framework for risk stratification and targeted intervention.