Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Cases. Jul 6, 2026; 14(19): 121056
Published online Jul 6, 2026. doi: 10.12998/wjcc.121056
Published online Jul 6, 2026. doi: 10.12998/wjcc.121056
Letter to the Editor: Ileocecal basidiobolomycosis resembling malignancy - histopathological insights and a justification for nonsurgical therapy
Tushar K Bhadra, Department of General Surgery, Dhaka Medical College, Dhaka 1000, Bangladesh
Brandon Lucke-Wold, Lillian S. Wells Department of Neurosurgery, University of Florida, Gainesville, FL 32608, United States
Co-first authors: Tushar K Bhadra and Brandon Lucke-Wold.
Author contributions: Bhadra TK and Lucke-Wold B contributed equally to this article, they are the co-first authors of this manuscript; Bhadra TK designed the overall concept and outline of the manuscript, and contributed to the writing and editing of the manuscript; Lucke-Wold B contributed to the discussion, design of the manuscript, and review of literature; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Brandon Lucke-Wold, MD, Lillian S. Wells Department of Neurosurgery, University of Florida, 1505 SW Archer Rd, Gainesville, FL 32608, United States. brandon.lucke-wold@neurosurgery.ufl.edu
Received: March 16, 2026
Revised: April 13, 2026
Accepted: June 4, 2026
Published online: July 6, 2026
Processing time: 110 Days and 12.2 Hours
Revised: April 13, 2026
Accepted: June 4, 2026
Published online: July 6, 2026
Processing time: 110 Days and 12.2 Hours
Core Tip
Core Tip: Gastrointestinal basidiobolomycosis is a rare fungal infection most seen in Iran, Saudi Arabia, and the desert areas of the United States. Unlike other fungal infections, it commonly occurs in immunocompetent individuals. Histopathological findings like the Splendore-Hoeppli phenomenon remains cornerstone of this infection diagnosis. While itraconazole is first line medication in most cases, posaconazole is utilized in treatment-refractory cases. Awareness should be raised in clinicians of endemic regions to consider gastrointestinal basidiobolomycosis as a differential diagnosis in patients presenting with an inflammatory ileocecal mass with eosinophilia.