Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Cases. Jun 26, 2026; 14(18): 121058
Published online Jun 26, 2026. doi: 10.12998/wjcc.121058
Published online Jun 26, 2026. doi: 10.12998/wjcc.121058
Challenges in the diagnosis and treatment of giant fibrovascular polyps of the esophagus: Two case reports
Petko Karagyozov, Ivelina Zhecheva, Kaloyan Ivanov, Clinic of Gastroenterology, Acibadem City Clinic University Hospital Tokuda, Sofia 1407, Bulgaria
Petko Karagyozov, Medical University, Pleven 5800, Bulgaria
Ivan Galev, Department of Clinical Patology, Acibadem City Clinic Tokuda University Hospital, Sofia 1407, Bulgaria
Co-corresponding authors: Petko Karagyozov and Ivelina Zhecheva.
Author contributions: Karagyozov P contributed to conceptualization and supervisio; Karagyozov P and Zhecheva I contributed to data curation and case management, investigation, writing-original draft, image acquisition and preparation, have played important and indispensable roles in the manuscript preparation as the co-corresponding authors; Ivanov K contributed to image acquisition; Galev I contributed to pathological analysis.
AI contribution statement: Only ChatGPT was used for grammar and language editing. No other artificial intelligence tools were employed. The entire content of the main text (abstract, introduction, materials and methods, results, discussion, and conclusion) or any part thereof was not generated by artificial intelligence. The entire scientific content of the manuscript was written by the author alone. All images were created by the author and no images generated by artificial intelligence were used.
Informed consent statement: Written informed consent was obtained from the patients for publication of this case report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors confirm that this case report has been prepared in accordance with the CARE guidelines (2016).
Corresponding author: Petko Karagyozov, MD, PhD, Professor, Department of Gastro
Received: March 16, 2026
Revised: March 21, 2026
Accepted: May 20, 2026
Published online: June 26, 2026
Processing time: 93 Days and 4.4 Hours
Revised: March 21, 2026
Accepted: May 20, 2026
Published online: June 26, 2026
Processing time: 93 Days and 4.4 Hours
Core Tip
Core Tip: Esophageal fibrovascular polyps (FVPs) are uncommon benign tumors that often remain asymptomatic until they grow to a substantial size. When symptomatic, they may cause dysphagia, regurgitation, bleeding, or even life-threatening airway obstruction. We report two cases of esophageal FVPs successfully managed by endoscopic submucosal dissection. These cases demonstrate that, in selected patients, endoscopic treatment can be considered a safe and effective minimally invasive alternative to surgery.