Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.
World J Clin Cases. May 26, 2026; 14(15): 120061
Published online May 26, 2026. doi: 10.12998/wjcc.v14.i15.120061
Published online May 26, 2026. doi: 10.12998/wjcc.v14.i15.120061
Benign but not inconsequential, paediatric sciatic nerve neuromuscular choristoma and its longitudinal impact: A case report
Karthik Saravanan, School of Medicine and Biomedical Sciences, Queen’s College, University of Oxford, Oxford OX1 4AW, United Kingdom
Palaniappan Ganesh Nagappan, Ashley Iain Simpson, Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, London HA7 4LP, United Kingdom
Author contributions: Saravanan K, Nagappan PG and Simpson AI were all equally involved with addressing the reviewer comments and implementing these into the edited manuscript for re-submission.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Ashley Iain Simpson, Consultant, FRCS, Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, Brockley Hill, London HA7 4LP, United Kingdom. ashley.simpson@nhs.net
Received: February 14, 2026
Revised: March 12, 2026
Accepted: April 22, 2026
Published online: May 26, 2026
Processing time: 88 Days and 6 Hours
Revised: March 12, 2026
Accepted: April 22, 2026
Published online: May 26, 2026
Processing time: 88 Days and 6 Hours
Core Tip
Core Tip: Neuromuscular choristoma (NMC) is a rare benign developmental lesion of peripheral nerves in which mature muscle fibres are intermingled with nerve fascicles. Although NMC is histologically benign, unnecessary surgical intervention can provoke an aggressive desmoid-type fibromatosis in the affected nerve. Paediatric sciatic nerve NMC cases are extremely uncommon, with only one published report providing long-term follow-up. We present an 11-year follow-up of a child with a sciatic NMC, underscoring the significant orthopaedic sequelae that can arise and necessitate complex multidisciplinary management. This under-recognised aspect of NMC care is a key clinical consideration highlighted by our case.