Small bowel ulcers and bleeding: An overlooked yet critical clinical challenge

doi:10.12998/wjcc.v13.i30.109445

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Oct 26, 2025 (publication date) through Oct 11, 2025

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Editorial

World J Clin Cases. Oct 26, 2025; 13(30): 109445
Published online Oct 26, 2025. doi: 10.12998/wjcc.v13.i30.109445

Small bowel ulcers and bleeding: An overlooked yet critical clinical challenge

Orivaldo Alves Barbosa

Orivaldo Alves Barbosa, Internal Medicine, Hospital Cesar Cals, Fortaleza 60810035, Ceara, Brazil

Author contributions: Barbosa OA performed the literature review and wrote the manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Orivaldo Alves Barbosa, MD, Chief Physician, Internal Medicine, Hospital Cesar Cals, Avenida do imperador 545, Fortaleza 60810035, Ceara, Brazil. orivaldo.alves.barbosa@gmail.com

Received: May 12, 2025
Revised: May 29, 2025
Accepted: August 13, 2025
Published online: October 26, 2025
Processing time: 153 Days and 12.2 Hours

Core Tip

Core Tip: Small bowel bleeding remains a challenging clinical entity due to its obscure presentation and broad differential diagnosis. This editorial highlights a rare but significant cause—ulcerated jejunal gastrointestinal stromal tumor (GIST)—emphasizing the aggressive behavior of small intestinal GISTs compared to gastric ones. It reinforces the need for a structured diagnostic approach, incorporating capsule endoscopy and enteroscopy, and alerts clinicians to consider both common and rare etiologies, including infectious and genetic causes, when managing small bowel ulcers and bleeding.