Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2025; 13(26): 108308
Published online Sep 16, 2025. doi: 10.12998/wjcc.v13.i26.108308
Thoughts and challenges of giant retroperitoneal liposarcoma: A case report
Li-Li Cheng, Biao Tang, Hui Liu, Fan Zhu, Yi-Fa Chen, Wei Zhang
Li-Li Cheng, Biao Tang, Hui Liu, Fan Zhu, Yi-Fa Chen, The First Department of General Surgery, Ezhou Central Hospital, Ezhou 436000, Hubei Province, China
Wei Zhang, Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 43000, Hubei Province, China
Author contributions: Cheng LL was responsible for the study design and manuscript writing; Biao T acquired medical images; Liu H and Zhu F assisted in the operation and clinical data collection; Zhang W performed the operation; Chen YF participated in the study design and manuscript revision; all the authors read and agreed to the final manuscript.
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Zhang, Chief Physician, Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jiefang Road, Wuhan 43000, Hubei Province, China. weizhangtjh@hust.edu.cn
Received: April 22, 2025
Revised: May 8, 2025
Accepted: May 28, 2025
Published online: September 16, 2025
Processing time: 92 Days and 17.3 Hours
Core Tip

Core Tip: Retroperitoneal liposarcoma (RPLS) is a rare malignant tumor. When its diameter exceeds 30 cm or its weight is no less than 20 kg, it is classified as giant RPLS, which significantly increases the complexity of surgical intervention. Giant RPLS may necessitate concomitant resection of adjacent organs and cannot be completely resected, leading to a high recurrence rate and suboptimal treatment outcomes.