©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 16, 2025; 13(17): 100741
Published online Jun 16, 2025. doi: 10.12998/wjcc.v13.i17.100741
Published online Jun 16, 2025. doi: 10.12998/wjcc.v13.i17.100741
Recurrent acute pancreatitis and primary hyperparathyroidism in patients presenting to the emergency department: Diagnostic challenges
Faruk Danış, Department of Emergency Medicine, Bolu Abant İzzet Baysal University Medical School, Bolu 14000, Türkiye
Emre Kudu, Department of Emergency Medicine, Marmara University Pendik Training and Research Hospital, İstanbul 34899, Türkiye
Co-first authors: Faruk Danış and Emre Kudu.
Author contributions: Danış F designed the overall concept, outline, and design of the manuscript; Kudu E contributed to the discussion, writing, editing of the manuscript, and review of the literature; and all authors approved the final version to be published.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Emre Kudu, MD, Department of Emergency Medicine, Marmara University Pendik Training and Research Hospital, Fevzi Çakmak, Muhsin Yazıcıoğlu Cd 10, İstanbul 34899, Türkiye. dr.emre.kudu@gmail.com
Received: August 24, 2024
Revised: January 19, 2025
Accepted: January 21, 2025
Published online: June 16, 2025
Processing time: 177 Days and 11.1 Hours
Revised: January 19, 2025
Accepted: January 21, 2025
Published online: June 16, 2025
Processing time: 177 Days and 11.1 Hours
Core Tip
Core Tip: Recurrent cases of acute pancreatitis can present a diagnostic challenge in the emergency department and are rarely caused by underlying endocrine disorders such as primary hyperparathyroidism (PHPT). PHPT can lead to hypercalcemia, increasing the risk of pancreatitis, which may present with less pronounced symptoms, especially in children. Emergency medicine clinicians should adopt a careful clinical assessment and multidisciplinary approach to differentiate rare etiologies, especially in cases of atypical pancreatitis. This case highlights that PHPT may be missed in pediatrics and suggests using high clinical suspicion and advanced imaging techniques to make the correct diagnosis.