©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2025; 13(14): 104039
Published online May 16, 2025. doi: 10.12998/wjcc.v13.i14.104039
Published online May 16, 2025. doi: 10.12998/wjcc.v13.i14.104039
Severe upper gastrointestinal hemorrhage due to milk protein allergy: A case report
Huan-Huan Jiang, Qing Tang, Li Huang, Xiang Yun, Qing-Wen Shan, Xiu-Qi Chen, Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, Guangxi Zhuang Autonomous Region, China
Author contributions: Jiang HH contributed to data collection, statistically analyzed, and drafting of the paper; Tang Q, Huang L, Yun X, and Shan QW performed data collection design and revision of the paper; Chen XQ contributed the conception and design of study and revised the final paper; and all authors approved the final submitted manuscript.
Supported by the Excellent Medical Talents Training Program of the First Affiliated Hospital of Guangxi Medical University, Difficult and Critical illness Center, Pediatric Clinical Medical Research Center of Guangxi, No. Gui Ke AD22035219; and the Key Laboratory of Children’s Disease Research in Guangxi’s Colleges and Universities, Education Department of Guangxi Zhuang Autonomous Region.
Informed consent statement: The verbal informed consent was obtained from all the parents or guardians of the patients involved.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Xiu-Qi Chen, Department of Pediatrics, The First Affiliated Hospital of Guangxi Medical University, Shuangyong Road, Nanning 530021, Guangxi Zhuang Autono
Received: December 8, 2024
Revised: December 21, 2024
Accepted: January 7, 2025
Published online: May 16, 2025
Processing time: 38 Days and 13 Hours
Revised: December 21, 2024
Accepted: January 7, 2025
Published online: May 16, 2025
Processing time: 38 Days and 13 Hours
Core Tip
Core Tip: Milk protein allergy is the most common food allergy reaction in infants and children under three years old, with diverse and non-specific clinical manifestations. Severe clinical symptoms such as gastrointestinal bleeding can be life-threatening, requiring doctors to be vigilant. This study, by reporting a case of severe milk protein allergy in children, will play a warning role in future clinical application.