©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2024; 12(22): 5067-5082
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.5067
Published online Aug 6, 2024. doi: 10.12998/wjcc.v12.i22.5067
Five commonly used traditional Chinese medicine formulas in the treatment of ulcerative colitis: A network meta-analysis
Zhi-Hui Zhao, Yi-Hang Dong, Xin-Qi Jiang, Jing Wang, Wan-Li Qin, Zhang-Yi Liu, Xiao-Qing Zhang, School of Life Sciences, Beijing University of Chinese Medicine, Beijing 102488, China
Yu-Jie Wei, School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 102488, China
Co-first authors: Zhi-Hui Zhao and Yu-Jie Wei.
Author contributions: Zhao ZH and Wei YJ contributed equally as co-first authors. Zhao ZH and Jiang XQ designed the research; Zhao ZH, Wei YJ, and Jiang XQ contributed to analytical tools and performed the analysis; Zhao ZH, Wei YJ, and Wang J analyzed the data; Zhao ZH, Dong YH, and Qin WL wrote the paper; Zhang XQ revised the manuscript and provided financial support.
Conflict-of-interest statement: The authors declare that there is no conflict of interest regarding the publication of this paper.
PRISMA 2009 Checklist statement: We have revised and filled out the document in accordance with the PRISMA 2009 Checklist.
Corresponding author: Xiao-Qing Zhang, PhD, Professor, School of Life Sciences, Beijing University of Chinese Medicine, No. 11 East Beisanhuan Road, Chaoyang District, Beijing 102488, China. 202001003@bucm.edu.cn
Received: February 19, 2024
Revised: April 26, 2024
Accepted: June 3, 2024
Published online: August 6, 2024
Processing time: 133 Days and 22.6 Hours
Revised: April 26, 2024
Accepted: June 3, 2024
Published online: August 6, 2024
Processing time: 133 Days and 22.6 Hours
Core Tip
Core Tip: This study aimed to evaluate the clinical efficacy and safety of commonly used traditional Chinese medicines (TCM) for the treatment of ulcerative colitis (UC), in clinical practice, through a network meta-analysis. A network meta-analysis of the five types of TCM formulas can provide a rational and personalized plan for the selection and use of TCM as clinical adjuvant therapy for UC. TCM formulas combined with mesalazine exhibit a better effect in treating UC compared to using mesalazine alone. The adjuvant treatment of UC with TCM formulas can improve clinical efficacy, repair the intestinal mucosa, improve the immunity of the body and the quality of life of patients, and reduce the probability of disease recurrence.