Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2024; 12(21): 4777-4782
Published online Jul 26, 2024. doi: 10.12998/wjcc.v12.i21.4777
Hysteroscopic cervical biopsy for women with persistent human papillomavirus infection after loop electrosurgical excision procedure: A case report
Hui Li, Shan-Shan Mei, Pei-Yu Mao, Xin-Yan Wang, Hua-Di Yang
Hui Li, Shan-Shan Mei, Pei-Yu Mao, Xin-Yan Wang, Hua-Di Yang, Department of Gynecology and Obstetrics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, Zhejiang Province, China
Author contributions: Li H was responsible for formal analysis, methodology, writing; Mei SS was responsible for visualization, writing; Mao PY was responsible for data curation, formal analysis, writing; Wang XY was responsible for formal analysis, writing; Yang HD was responsible for methodology, project administration, supervision, writing, review and editing.
Supported by 2024 Natural Science Joint Foundation of Zhejiang Province, No. LBY24H040007.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and all accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: We have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hua-Di Yang, MD, Doctor, Department of Gynecology and Obstetrics, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), No. 54 Youdian Road, Shangcheng District, Hangzhou 310006, Zhejiang Province, China. rani712@163.com
Received: April 8, 2024
Revised: May 11, 2024
Accepted: June 20, 2024
Published online: July 26, 2024
Processing time: 84 Days and 0.5 Hours
Core Tip

Core Tip: The loop electrosurgical excision procedure (LEEP) is widely used to treat human papillomavirus (HPV)-mediated disease; thus, cervical cancer is highly preventable. However, LEEP does not necessarily clear HPV infection rapidly, and patients with persistent HPV infection after LEEP are at risk of cervical cancer. The formation of cervical scars after LEEP may affect the accuracy of ThinPrep cytology test and cervical biopsy results; thus, hysteroscopic resection of cervical canal tissue is recommended as a supplement to cervical biopsy because it helps define the lesion site and may yield a pathologic diagnosis.