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©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jun 6, 2024; 12(16): 2847-2855
Published online Jun 6, 2024. doi: 10.12998/wjcc.v12.i16.2847
Published online Jun 6, 2024. doi: 10.12998/wjcc.v12.i16.2847
Conversion therapy of a giant hepatocellular carcinoma with portal vein thrombus and inferior vena cava thrombus: A case report and review of literature
Wen-Jie Song, Jian Xu, Ye Nie, Wei-Min Li, Kai-Shan Tao, Department of Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, Xi'an 710032, Shaanxi Province, China
Jian-Ping Li, Department of Radiotherapy, The First Affiliated Hospital of the Fourth Military Medical University, Xi'an 710032, Shaanxi Province, China
Li Yang, State Key Laboratory of Cancer Biology, Department of Pathology, Xijing Hospital and School of Basic Medicine, Xijing Hospital, Air Force Medical University, Xi'an 710000, Shaanxi Province, China
Meng-Qi Wei, Department of Radiology, Xijing Hospital, Air Force Medical University, Xi'an 710032, Shaanxi Province, China
Author contributions: Song WJ, Xu J, Nie Y, Li WM, Li JJ, Yang L, Wei MQ and Tao KS analyzed the data and wrote the manuscript; All authors have read and approve the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for the use of this case report and any accompanying images.
Conflict-of-interest statement: All authors have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kai-Shan Tao, MD, PhD, Chief Doctor, Chief Physician, Hepatobiliary Surgery, Xijing Hospital, Air Force Medical University, No. 127 Changle West Road, Xincheng District, Xi'an 710032, Shaanxi Province, China. taokaishan0726@163.com
Received: December 24, 2023
Revised: February 25, 2024
Accepted: April 11, 2024
Published online: June 6, 2024
Processing time: 157 Days and 1 Hours
Revised: February 25, 2024
Accepted: April 11, 2024
Published online: June 6, 2024
Processing time: 157 Days and 1 Hours
Core Tip
Core Tip: In this case, atezolizumab, bevacizumab, icaritin soft capsules combined with radiotherapy and transcatheter arterial chemoembolization had a good effect. For patients with hepatocellular carcinoma combined with hepatic vein/inferior vena cava tumor thrombus, adopting a high-intensity, multimodal proactive strategy under the guidance of multidisciplinary team is an important attempt to break through the current treatment dilemma.