©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. May 16, 2024; 12(14): 2304-2307
Published online May 16, 2024. doi: 10.12998/wjcc.v12.i14.2304
Published online May 16, 2024. doi: 10.12998/wjcc.v12.i14.2304
Investigating causal links between gastroesophageal reflux disease and essential hypertension
Gowthami Sai Kogilathota Jagirdhar, Department of Medicine, Saint Francis Health Science Center, Newark, NJ 07107, United States
Yatinder Bains, Department of Gastroenterology, Saint Michaels Medical Center, Newark, NJ 07102, United States
Salim Surani, Department of Medicine and Pharmacology, Texas A&M University, College Station, TX 77843, United States
Author contributions: Surani S and Bains Y designed the overall concept and outline of the manuscript; Jagirdhar GSK and Bains Y contributed to the discussion and design of the manuscript; Jagirdhar GSK, Bains Y and Surani S contributed to the writing, editing the manuscript and review of literature.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Salim Surani, FASP, MD, FCCP, MHSc, Adjunct Professor, Department of Medicine and Pharmacology, Texas A&M University, 40 Bizzell Street, College Station, TX 77843, United States. srsurani@hotmail.com
Received: February 14, 2024
Revised: March 17, 2024
Accepted: April 3, 2024
Published online: May 16, 2024
Processing time: 80 Days and 20.1 Hours
Revised: March 17, 2024
Accepted: April 3, 2024
Published online: May 16, 2024
Processing time: 80 Days and 20.1 Hours
Core Tip
Core Tip: The relationship between gastroesophageal reflux disease (GERD) and hypertension (HTN) is multifaceted, involving mechanisms such as autonomic dysfunction, nitric oxide levels, and medication effects. GERD treatment, including anti-reflux surgery, may improve HTN control, highlighting the clinical relevance of understanding this asso