Can we triumph over locally advanced cervical cancer with colossal para-aortic lymph nodes? A case report

doi:10.12998/wjcc.v12.i10.1851

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Apr 6, 2024 (publication date) through Mar 2, 2026

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Report

World J Clin Cases. Apr 6, 2024; 12(10): 1851-1856
Published online Apr 6, 2024. doi: 10.12998/wjcc.v12.i10.1851

Can we triumph over locally advanced cervical cancer with colossal para-aortic lymph nodes? A case report

Abdulla Alzibdeh, Issa Mohamad, Lina Wahbeh, Ramiz Abuhijlih, Fawzi Abuhijla

Abdulla Alzibdeh, Issa Mohamad, Lina Wahbeh, Ramiz Abuhijlih, Fawzi Abuhijla, Department of Radiation Oncology, King Hussein Cancer Center, Amman 11941, Jordan

Author contributions: Alzibdeh A and Abuhijla F designed research concept, reviewed the literature and wrote the manuscript; all author have edited the manuscript; all authors have read and approved the final version of the manuscript.

Informed consent statement: Informed consent obtained from the patient.

Conflict-of-interest statement: All authors declare no conflict of interest.

CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).

Corresponding author: Fawzi Abuhijla, MD, MSc, Assistant Professor, Department of Radiation Oncology, King Hussein Cancer Center, Queen Rania St. PO Box 1269, Amman 11941, Jordan. fhijle@khcc.jo

Received: January 23, 2024
Peer-review started: January 23, 2024
First decision: January 31, 2024
Revised: February 4, 2024
Accepted: March 18, 2024
Article in press: March 18, 2024
Published online: April 6, 2024
Processing time: 69 Days and 14.5 Hours

Core Tip

Core Tip: In rare case of locally advanced cervical cancer with massive para-aortic lymph node involvement, we demonstrated successful treatment with concurrent chemoradiotherapy, achieving a complete response without surgery. Our study underscores the challenge of managing such cases because of the limited evidence on the optimal radiation doses for bulky lymph nodes. Despite this, our case highlights the potential efficacy of high-dose radiation, and the importance of multidisciplinary collaboration in treatment planning. Further research is warranted to refine treatment strategies and improve outcomes in similar cases.