Rare case of lupus enteritis presenting as colorectum involvement: A case report and review of literature

Core Tip

Core Tip: According to the 2019 Classification criteria for systemic lupus erythematosus of the European League Against Rheumatism/American College of Rheumatology classification criteria, the score of this case was 14. In addition, computed tomography of abdomen showed marked and dramatic wall edema of the whole colon and rectum, ischemia and hyperemia of ascending colon intestinal wall, engorgement of mesenteric vessels, increased attenuation of mesenteric fat, ascites and bilateral ureter-hydronephrosis, demonstrating colon and rectum lupus enteritis (LE). Moreover, laboratory tests revealed lower complement C3 and C4. The titer of antinuclear antibody was 1:100. Overall, whole colon and rectum LE invaded of this case without involving small intestine was clear which was one of the rare manifestations of Systemic lupus erythematosus (SLE). The patient was treated with 10 mg methylprednisolone sodium succinate and 100 mL of 0.9% sodium chloride, hydroxychloroquine (100 mg) and nutrition support. After one week therapy of methylprednisolone and hydroxychloroquine, her symptoms and disease activity of SLE were dramatically improved.