Case Report
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Aug 6, 2023; 11(22): 5303-5308
Published online Aug 6, 2023. doi: 10.12998/wjcc.v11.i22.5303
Recurrent ventricular arrhythmia due to aconite intoxication successfully treated with landiolol: A case report
Chiaki Matsuo, Koji Yamamoto, Hidetada Fukushima, Daisuke Yajima, Hiroyuki Inoue
Chiaki Matsuo, Koji Yamamoto, Hidetada Fukushima, Department of Emergency and Critical Care Medicine, Nara Medical University, Kashihara City 634-8522, Nara, Japan
Daisuke Yajima, Hiroyuki Inoue, Department of Forensic Medicine, School of Medicine, International University of Health and Welfare, Narita City 286-8686, Chiba, Japan
Author contributions: Matsuo C wrote the manuscript and prepared the figures; Yamamoto K and Fukushima H conceptualized and designed the study and critically revised the manuscript; Yajima D and Inoue H contributed to the analysis of the patient’s serum samples; all authors read and approved the final manuscript.
Informed consent statement: Informed consent was obtained from the patient to publish the report and associated images.
Conflict-of-interest statement: All the authors declare no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Koji Yamamoto, MD, Doctor, Department of Emergency and Critical Care Medicine, Nara Medical University, 840 Shijotyo, Kashihara City 634-8522, Nara, Japan. k.yamamoto@naramed-u.ac.jp
Received: May 18, 2023
Peer-review started: May 18, 2023
First decision: June 21, 2023
Revised: July 1, 2023
Accepted: July 17, 2023
Article in press: July 17, 2023
Published online: August 6, 2023
Processing time: 77 Days and 0 Hours
Core Tip

Core Tip: Aconite is a well-known plant that contains highly toxic aconitines. Ventricular arrhythmias such as ventricular tachycardia and fibrillation are the main causes of death in patients with aconite poisoning. We encountered a case of polymorphic ventricular arrhythmia that occurred after aconite ingestion. This is the first case where landiolol successfully suppressed ventricular arrhythmia caused by aconite intoxication. Our study suggests that landiolol may be an alternative treatment for amiodarone-refractory ventricular arrhythmias caused by aconite intoxication and can improve the clinical outcomes of patients with aconite intoxication.