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Case Report
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jan 6, 2023; 11(1): 187-192
Published online Jan 6, 2023. doi: 10.12998/wjcc.v11.i1.187
Hyponatremic encephalopathy due to polyethylene glycol-based bowel preparation for colonoscopy: A case report
Yuan Zhao, Hai-Sheng Dong
Yuan Zhao, Hai-Sheng Dong, Department of Critical Care Medicine, Shanghai TCM-integrated Hospital, Shanghai 200082, China
Author contributions: Zhao Y and Dong HS designed the study; Zhao Y performed the study, collected and analyzed the data and wrote the manuscript; All authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient after treatment for publication of this case report and any accompanying images. A copy of the written consent is available for review by the Editor of this journal.
Conflict-of-interest statement: All authors report having no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Hai-Sheng Dong, MD, Doctor, Department of Critical Care Medicine, Shanghai TCM-integrated Hospital, No. 230 Baoding Road, Hongkou District, Shanghai 200082, China. hsdong06@163.com
Received: September 23, 2022
Peer-review started: September 23, 2022
First decision: October 30, 2022
Revised: November 11, 2022
Accepted: December 21, 2022
Article in press: December 21, 2022
Published online: January 6, 2023
Processing time: 103 Days and 18.6 Hours
Core Tip

Core Tip: Hyponatremic encephalopathy caused by the use of polyethylene glycol (PEG) solution for intestinal cleaning is rare, which can lead to irreversible sequelae and even death. This case is a female with neurological dysfunction due to hyponatremia induced by the use of pegylated for bowel preparation before colonoscopy. The patient was in a coma with the brain suggesting cerebral edema, and was transferred to the intensive care unit for treatment with 3% sodium chloride injection. The patient's medical history should be fully understood before using PEG for bowel preparation, as both untimely and overtreatment can lead to serious complications.

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