©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 26, 2022; 10(9): 2864-2870
Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2864
Published online Mar 26, 2022. doi: 10.12998/wjcc.v10.i9.2864
Laninamivir-induced ischemic enterocolitis: A case report
Chihiro Suzuki, Tsuneaki Kenzaka, Department of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tanba 669-3495, Japan
Tsuneaki Kenzaka, Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Kobe 652-0032, Japan
Author contributions: Suzuki C managed the case and redaction and correction of the manuscript; Kenzaka T assisted with redaction, correction, and reconstruction of the manuscript; All authors read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor of this journal.
Conflict-of-interest statement: The authors declare that they have no competing interests.
CARE Checklist (2016) statement: The authors have read the CARE Checklist statement, and the manuscript was prepared and revised according to the CARE Checklist statement.
Corresponding author: Tsuneaki Kenzaka, PhD, Professor, Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, Division of Community Medicine and Career Development, Kobe University Graduate School of Medicine, 2-1-5, Arata-cho, Hyogo-ku, Kobe, Hyogo 652-0032, Japan.
Received: September 10, 2021
Peer-review started: September 10, 2021
First decision: October 25, 2021
Revised: October 29, 2021
Accepted: February 12, 2022
Article in press: February 12, 2022
Published online: March 26, 2022
Processing time: 193 Days and 0.3 Hours
Peer-review started: September 10, 2021
First decision: October 25, 2021
Revised: October 29, 2021
Accepted: February 12, 2022
Article in press: February 12, 2022
Published online: March 26, 2022
Processing time: 193 Days and 0.3 Hours
Core Tip
Core Tip: Although a clear mechanism underlying oseltamivir-associated hemorrhagic enteritis/ischemic enterocolitis has not been elucidated, the simultaneous occurrence of the following two factors has been considered responsible for the condition: (1) Local angiospasm and vasculitis due to the effect of an allergic reaction to oseltamivir; and (2) Hypoperfusion in the intestinal tract due to the effect of dehydration caused by influenza. Laninamivir is considered to demonstrate the same mechanism as oseltamivir.