©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Mar 16, 2022; 10(8): 2369-2381
Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2369
Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2369
Developing natural marine products for treating liver diseases
Qian Wei, Jin-Sheng Guo, Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
Author contributions: Qian W drafted the manuscript; Guo JS conceptualized and revised the manuscript; all authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China , No. 91129705, No. 81070340, and No. 30570825.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Corresponding author: Jin-Sheng Guo, FAASLD, MD, Chief Doctor, Chief Physician, Professor, Department of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, No. 180 Feng Lin Road, Shanghai 200032, China. guo.jinsheng@zs-hospital.sh.cn
Received: August 4, 2021
Peer-review started: August 4, 2021
First decision: September 4, 2021
Revised: September 14, 2021
Accepted: January 29, 2022
Article in press: January 29, 2022
Published online: March 16, 2022
Processing time: 218 Days and 9.5 Hours
Peer-review started: August 4, 2021
First decision: September 4, 2021
Revised: September 14, 2021
Accepted: January 29, 2022
Article in press: January 29, 2022
Published online: March 16, 2022
Processing time: 218 Days and 9.5 Hours
Core Tip
Core Tip: The prevalence of liver diseases has been rising worldwide, especially non-alcoholic fatty liver disease that is associated with increasingly urbanized lifestyles and dietary changes. Effective and cost-efficient drugs and medicine food homology are needed in concert with improving liver health. Marine sources are rich and play an important role in the generation of unique drugs. A number of marine-derived compounds are proven to improve lipid metabolism, modulate the gut microbiota, prevent reactive oxygen species formation, and possess anti-inflammatory and anticancer activities, which means that they can be an invaluable source for the discovery of new compounds for the prevention and treatment of liver diseases.