Case Report
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Nov 6, 2022; 10(31): 11638-11645
Published online Nov 6, 2022. doi: 10.12998/wjcc.v10.i31.11638
Pancreatic paraganglioma with multiple lymph node metastases found by spectral computed tomography: A case report and review of the literature
Ting Li, Rong-Qi Yi, Gang Xie, Dan-Ni Wang, Yi-Tao Ren, Kang Li
Ting Li, Gang Xie, Department of Medical Imaging, North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Rong-Qi Yi, Kang Li, Department of Radiology, Chongqing General Hospital, Chongqing 401147, China
Dan-Ni Wang, Yi-Tao Ren, Department of Medical Imaging, Chongqing Medical University, Chongqing 400016, China
Author contributions: Li T and Yi RQ contributed to manuscript writing and editing, and data collection; Xie G was responsible for table preparation and data analysis; Wang DN and Ren YT provided processed image data and interpretation; Li K checked the manuscript and provided suggestions for revision; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kang Li, MD, Chief Doctor, Professor, Department of Radiology, Chongqing General Hospital, No. 118 Xingguang Avenue, Liangjiang New Area, Chongqing 401147, China. lkrmyydoctor@126.com
Received: July 21, 2022
Peer-review started: July 21, 2022
First decision: August 19, 2022
Revised: August 29, 2022
Accepted: October 9, 2022
Article in press: October 9, 2022
Published online: November 6, 2022
Processing time: 97 Days and 15.9 Hours
Core Tip

Core Tip: Primary pancreatic paraganglioma is an exceedingly rare, generally benign tumor, with only four cases of malignancy reported. They are often misdiagnosed as pancreatic neuroendocrine tumors (pNETs). Early filling of the draining veins may be a crucial imaging feature to differentiate pancreatic paraganglioma from pNETs and may be observed more frequently in malignant cases. Surgical resection is the primary treatment modality. However, the rich vascularity and potential functionality of the tumor pose a significant risk for invasive surgery. Thorough preoperative evaluation and preparation are necessary. Definitive diagnosis relies primarily on histopathological examination.