©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Sep 16, 2022; 10(26): 9241-9253
Published online Sep 16, 2022. doi: 10.12998/wjcc.v10.i26.9241
Published online Sep 16, 2022. doi: 10.12998/wjcc.v10.i26.9241
Early diagnostic value of liver stiffness measurement in hepatic sinusoidal obstruction syndrome induced by hematopoietic stem cell transplantation
You-Wen Tan, Yi-Chun Shi, Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, Zhenjiang 212003, Jiangsu Province, China
Author contributions: Tan YW and Shi YC wrote and revised the manuscript; and approved the final version to be published.
Conflict-of-interest statement: All authors have no conflicts of interest related to this manuscript.
Corresponding author: You-Wen Tan, MD, Chief Doctor, Professor, Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, No. 300 Daijiamen, Runzhou Distinct, Zhenjiang 212003, Jiangsu Province, China. tyw915@sina.com
Received: June 2, 2022
Peer-review started: June 2, 2022
First decision: June 18, 2022
Revised: June 27, 2022
Accepted: August 6, 2022
Article in press: August 6, 2022
Published online: September 16, 2022
Processing time: 91 Days and 21.3 Hours
Peer-review started: June 2, 2022
First decision: June 18, 2022
Revised: June 27, 2022
Accepted: August 6, 2022
Article in press: August 6, 2022
Published online: September 16, 2022
Processing time: 91 Days and 21.3 Hours
Core Tip
Core Tip: Clinical diagnosis of hematopoietic stem cell transplantation (HSCT)-sinusoidal obstruction syndrome (SOS) is based on the revised Seattle or Baltimore standards. Eight studies have shown the value of liver stiffness measurement (LSM) in the early diagnosis of HSCT-SOS. Four studies investigated the specificity and sensitivity of LSM for the early diagnosis of HSCT-SOS. Therefore, LSM can distinguish SOS from other post-HSCT complications, enabling a clear differential diagnosis. The early diagnosis of SOS is beneficial in preventing severe HSCT complications.