©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 16, 2022; 10(20): 6981-6990
Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.6981
Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.6981
Schwannomatosis patient who was followed up for fifteen years: A case report
Kai Li, Si-Jing Liu, Huai-Bo Wang, Chang-Yu Yin, Yong-Sheng Huang, Wei-Tao Guo, Department of Spine Surgery, The Second Hospital affiliated to Guangdong Medical University, Zhanjiang 524000, Guangdong Province, China
Author contributions: Li K analyzed the relevant literature and wrote the manuscript; Guo WT led the whole process, including 6 operations, and directed the writing of the manuscript; Liu SJ and Wang HB participated in the operations and collected data; Yin CY and Huang YS were responsible for the long-term follow-up of the patients.
Supported by Science and Technology Project of Zhanjiang City , No. 2018B01015 .
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors report no relevant conflict of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared according to the CARE Checklist (2016).
Corresponding author: Wei-Tao Guo, MD, PhD, Chief Doctor, Department of Spine Surgery, The Second Hospital affiliated to Guangdong Medical University, No. 12 Xiashan District Minyou Road, Zhanjiang 524000, Guangdong Province, China. kai376549128@163.com
Received: October 30, 2021
Peer-review started: October 30, 2021
First decision: March 23, 2022
Revised: April 5, 2022
Accepted: June 4, 2022
Article in press: June 4, 2022
Published online: July 16, 2022
Processing time: 247 Days and 8.5 Hours
Peer-review started: October 30, 2021
First decision: March 23, 2022
Revised: April 5, 2022
Accepted: June 4, 2022
Article in press: June 4, 2022
Published online: July 16, 2022
Processing time: 247 Days and 8.5 Hours
Core Tip
Core Tip: Schwannomatosis is a rare disease characterized by multiple schwannomas throughout the body. There are only a few reports of clinical cases of schwannomatosis. Here, we describe a patient who has been followed up for 15 years and has been treated with surgery 6 times. According to the family history, magnetic resonance imaging scan results, immunohistochemistry results and larger sequencing results, the patient was confirmed to have schwannomatosis. We summarized and discussed this case and reviewed the literature on the pathogenesis, clinical manifestations, clinical diagnosis and treatment of schwannomatosis.