Meta-Analysis
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Apr 16, 2022; 10(11): 3436-3448
Published online Apr 16, 2022. doi: 10.12998/wjcc.v10.i11.3436
Accuracy of ultrasound elastography for predicting breast cancer response to neoadjuvant chemotherapy: A systematic review and meta-analysis
Wei Chen, Li-Xiang Fang, Hai-Lan Chen, Jian-Hua Zheng
Wei Chen, Li-Xiang Fang, Hai-Lan Chen, Jian-Hua Zheng, Department of Ultrasound, The Affiliated Hospital of Putian University, Putian 351100, Fujian Province, China
Author contributions: Chen W and Zheng JH conceived and designed the study; Fang LX, Chen HL, and Zheng JH were involved in literature search and data collection; Chen W analyzed the data and wrote the paper; Zheng JH reviewed and edited the manuscript; all authors read and approved the final manuscript.
Conflict-of-interest statement: The authors deny any conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 checklist and the manuscript was prepared and revised according to the PRISMA 2009 checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Hua Zheng, MD, Doctor, Department of Ultrasound, The Affiliated Hospital of Putian University, No. 999 Dongzhen East Road, Putian 351100, Fujian Province, China. zhengjh0328@sina.com
Received: September 12, 2021
Peer-review started: September 12, 2021
First decision: October 25, 2021
Revised: November 9, 2021
Accepted: January 13, 2022
Article in press: January 13, 2022
Published online: April 16, 2022
Processing time: 208 Days and 3.8 Hours
Core Tip

Core Tip: Several studies have reported the prognostic value of ultrasound elastography (UE) in patients receiving neoadjuvant chemotherapy (NACT) for breast cancer. However, the assessment of parameters differed between shear-wave elastography and strain elastography in terms of measured elasticity parameter and mode of imaging. It is important, therefore, to assess the accuracy of the two modes of elastography. We assessed the accuracy of UE for predicting the pathologic complete response (pCR) in breast cancer patients following NACT. Strain-wave type of UE can accurately predict the pCR following NACT amongst breast cancer patients. Studies exploring its accuracy in different ethnic populations are required to strengthen the evidence.