Yu XQ, Deng HB, Liu Y, Qu C, Duan ZH, Tong ZH, Liu YX, Li WQ. Serum magnesium level as a predictor of acute kidney injury in patients with acute pancreatitis. World J Clin Cases 2021; 9(35): 10899-10908 [PMID: 35047600 DOI: 10.12998/wjcc.v9.i35.10899]
Corresponding Author of This Article
Wei-Qin Li, MD, Professor, Medical School, Southeast University, No. 87 Dingjiaqiao, Gulou District, Nanjing 210009, Jiangsu Province, China. liweiqindr@nju.edu.cn
Research Domain of This Article
Critical Care Medicine
Article-Type of This Article
Retrospective Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Yu XQ, Deng HB, Liu Y, Qu C, Duan ZH, Tong ZH, Liu YX, Li WQ. Serum magnesium level as a predictor of acute kidney injury in patients with acute pancreatitis. World J Clin Cases 2021; 9(35): 10899-10908 [PMID: 35047600 DOI: 10.12998/wjcc.v9.i35.10899]
World J Clin Cases. Dec 16, 2021; 9(35): 10899-10908 Published online Dec 16, 2021. doi: 10.12998/wjcc.v9.i35.10899
Serum magnesium level as a predictor of acute kidney injury in patients with acute pancreatitis
Xian-Qiang Yu, Hong-Bin Deng, Yang Liu, Cheng Qu, Ze-Hua Duan, Zhi-Hui Tong, Yu-Xiu Liu, Wei-Qin Li
Xian-Qiang Yu, Wei-Qin Li, Medical School, Southeast University, Nanjing 210009, Jiangsu Province, China
Hong-Bin Deng, Department of Critical Care Medicine, Nanjing Medical University, Nanjing 210002, Jiangsu Province, China
Yang Liu, Cheng Qu, Ze-Hua Duan, Department of Critical Care Medicine, Nanjing University, Nanjing 210002, Jiangsu Province, China
Zhi-Hui Tong, Yu-Xiu Liu, Wei-Qin Li, Department of Critical Care Medicine, General Hospital of Eastern Theater Command, Nanjing 210002, Jiangsu Province, China
Author contributions: Yu XQ and Deng HB made equal contributions to the article; Yu XQ and Deng HB completed the design and writing of the paper; Liu Y, Qu C, Duan ZH and Tong ZH participated in the revision and design of the article; Liu YX and Li WQ participated in the overall design and revision of the paper.
Supported byNational Natural Science Foundation of China, No. 82070669.
Institutional review board statement: The study was reviewed and approved by the Nanjing Jinling Hospital Institutional Review Board.
Informed consent statement: All authors have agreed to publish this article.
Conflict-of-interest statement: The authors declare that they have no competing interests.
Data sharing statement: The datasets used or analyzed during the current study are available from the corresponding author on reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Received: June 30, 2021 Peer-review started: June 30, 2021 First decision: August 19, 2021 Revised: September 1, 2021 Accepted: October 31, 2021 Article in press: October 31, 2021 Published online: December 16, 2021 Processing time: 163 Days and 2.8 Hours
ARTICLE HIGHLIGHTS
Research background
There is a lack of effective predictors of acute kidney injury (AKI) after acute pancreatitis (AP) in clinical practice.
Research motivation
To investigate the association between serum Mg2+ on admission and AKI after AP.
Research objectives
To determine whether serum Mg2+ is a valid predictor of AP-associated AKI using clinical data from our severe acute pancreatitis center.
Research methods
Our center is one of the largest severe acute pancreatitis treatment centers in China. A total of 233 patients with AP from August 2015 to February 2019 were included in a retrospective analysis. Almost all clinical and laboratory indicators were included in the study.
Research results
Lower serum Mg2+ was correlated with the occurrence of AKI (62.1% vs 21.2%, P < 0.001). Patients in the low serum Mg2+ level group had a longer intensive care unit (P < 0.001) and hospital stay (P < 0.001).
Research conclusions
Serum Mg2+ on admission can effectively predict AKI in AP patients.
Research perspectives
This study provides ideas and a basis for prospective observation of AKI after AP, and provides early warning for effective intervention of the disease.
