Scrotal septal flap and two-stage operation for complex hypospadias: A retrospective study

doi:10.12998/wjcc.v9.i13.2983

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World Journal of Clinical Cases

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Retrospective Study

World J Clin Cases. May 6, 2021; 9(13): 2983-2993
Published online May 6, 2021. doi: 10.12998/wjcc.v9.i13.2983

Scrotal septal flap and two-stage operation for complex hypospadias: A retrospective study

Sen Chen, Zhe Yang, Ning Ma, Wei-Xin Wang, Li-Si Xu, Qi-Yu Liu, Yang-Qun Li

Sen Chen, Zhe Yang, Ning Ma, Wei-Xin Wang, Li-Si Xu, Qi-Yu Liu, Yang-Qun Li, The 2^nd Department of Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100144, China

Author contributions: Chen S performed study design, data collection, data analysis, data interpretation, manuscript drafting, manuscript revision; Yang Z and Li YQ performed study design, data collection, data analysis, data interpretation, manuscript drafting, literature analysis, funds collection, manuscript revision; Ma N, Wang WX, Xu LS and Liu QY performed study design, data collection, data analysis; all authors have read and approved the manuscript.

Supported by Special Research Fund for Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. B2018009; and Beijing Municipal Science & Technology Commission-Functional Urethral Reconstruction of Hypospadias by Tissue Transplantation, No. Z161100000516015.

Institutional review board statement: This study was approved by the Medical Ethics Review Board of the Plastic Surgery Hospital, Chinese Academy of Medical Sciences (CAMS), and Peking Union Medical College (PUMC), No. ZX201968.

Informed consent statement: Written Informed consent was obtained from the study participants.

Conflict-of-interest statement: The authors have no conflict of interest to disclose.

Data sharing statement: The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.

Corresponding author: Yang-Qun Li, MD, Doctor, The 2^nd Department of Plastic Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 33 Badachu Road, Shijingshan District, Beijing 100144, China. liyangqundoctor@163.com

Received: September 10, 2020
Peer-review started: September 10, 2020
First decision: December 28, 2020
Revised: January 10, 2021
Accepted: February 11, 2021
Article in press: February 11, 2021
Published online: May 6, 2021
Processing time: 224 Days and 10.4 Hours

ARTICLE HIGHLIGHTS

Research background

Complex hypospadias is a surgical challenge and all kinds of graft tissues have several disadvantages.

Research motivation

A scrotal septal pedicle flap was used instead of a random flap to achieve a reliable blood supply.

Research objectives

To present the long-term outcomes of two-stage repair of complex hypospadias using a scrotal septal flap.

Research methods

This retrospective study included patients with complex hypospadias using a scrotal septal flap or prepuce flap, and compared the maximal/average urinary flow rates after surgery.

Research results

The maximal urinary flow rate, average urinary flow rate and the proportion of patients achieving good therapeutic effects were higher in the scrotal group. The scrotal flap two-stage surgery was independently associated with a higher maximal urinary flow rate and a higher average flow rate.

Research conclusions

The scrotal septal flap could be a versatile and reliable option for resurfacing the penis in patients undergoing complex hypospadias repair.

Research perspectives

This flap could be especially suitable for re-operative hypospadias in which prepuce tissue is limited.