Chen Q, Cao H, Zhang GC, Chen LW, Xu F. Successful totally transthoracic echocardiography guided transcatheter device closure of atrial septal defect in pregnant women. World J Clin Cases 2019; 7(6): 734-741 [PMID: 30968038 DOI: 10.12998/wjcc.v7.i6.734]
Corresponding Author of This Article
Qiang Chen, MD, Doctor, Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, No. 29 Xinquan Road, Fuzhou 350001, Fujian Province, China. chenqiang2228@163.com
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
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World J Clin Cases. Mar 26, 2019; 7(6): 734-741 Published online Mar 26, 2019. doi: 10.12998/wjcc.v7.i6.734
Successful totally transthoracic echocardiography guided transcatheter device closure of atrial septal defect in pregnant women
Qiang Chen, Hua Cao, Gui-Can Zhang, Liang-Wan Chen, Fan Xu
Qiang Chen, Hua Cao, Gui-Can Zhang, Liang-Wan Chen, Fan Xu, Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou 350001, Fujian Province, China
Author contributions: Chen Q and Cao H contributed equally to this study and are co-first authors; Chen Q and Cao H contributed to study conception and design; Zhang GC and Xu F contributed to data acquisition, analysis, and interpretation, and writing of the article; Chen Q, Cao H, Zhang GC, Chen LW, and Xu F contributed to the editing and final approval of the article.
Supported byChinese National and Fujian Provincial Key Clinical Specialty Construction Programs.
Institutional review board statement: The present study was approved by the Ethics Committee of Fujian Medical University, China and adhered to the tenets of the Declaration of Helsinki.
Informed consent statement: All patients were counseled on the potential maternal and fetal risks associated with the pregnancy, and all signed a consent form to undergo transcatheter device closure of ASD.
Conflict-of-interest statement: None.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Corresponding author: Qiang Chen, MD, Doctor, Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, No. 29 Xinquan Road, Fuzhou 350001, Fujian Province, China. chenqiang2228@163.com
Telephone: +86-591-83344034
Received: December 20, 2018 Peer-review started: December 20, 2018 First decision: January 19, 2019 Revised: February 1, 2019 Accepted: February 18, 2019 Article in press: February 18, 2019 Published online: March 26, 2019 Processing time: 96 Days and 18.7 Hours
ARTICLE HIGHLIGHTS
Research background
Transcatheter device closure of atrial septal defect (ASD) guided by fluoroscopy and/or transesophageal echocardiography is a mature technology. Little study has focused on whether the technology can be guided totally by transthoracic echocardiography (TTE), even in pregnant women with ASD.
Research motivation
To evaluate the safety and efficacy of totally TTE guided transcatheter device closure of ASD in pregnant women.
Research objectives
We want to prove that our procedure may be performed as another choice for pregnant women with ASD.
Research methods
Six pregnant women (gestational age 20-26 wk) with ASD underwent transcatheter device closure totally guided by TTE at our cardiac center from January 2015 to August 2017. A routine transcatheter procedure without fluoroscopy or intubation and a domestic occluder were used in this study.
Research results
All six patients had successful closure with good clinical results, and the overall immediate complete closure rate was 100%. The size of the occluder deployed ranged from 20 to 32 mm (26.7 ± 4.3 mm), the procedure time ranged from 30 to 50 min (41.7 ± 7.5 min), and the length of hospital stay was 2-3 d (mean 2.2 ± 0.4 d). There were no serious cardiovascular related complications.
Research conclusions
Totally TTE guided transcatheter device closure of ASD in pregnant women may be safe and effective.
Research perspectives
Transcatheter device closure of ASD totally guided by TTE may be an alternative treatment for pregnant women with ASD.
