Published online Oct 6, 2018. doi: 10.12998/wjcc.v6.i11.477
Peer-review started: June 11, 2018
First decision: June 20, 2018
Revised: July 30, 2018
Accepted: August 12, 2018
Article in press: August 12, 2018
Published online: October 6, 2018
Processing time: 110 Days and 0.8 Hours
A 36-year-old male with symptoms of recurrent abdominal pain and intermittent right eyelid oedema exhibiting space-occupying lesions in the pancreas and orbit.
Isolated myeloid sarcoma.
Pancreatitis, pancreatic cancer, and lymphoma should be excluded.
Normal tumour marker levels, slightly elevated liver and pancreatic enzymes, and normal routine blood and autoantibody test results.
A malignant tumour positive for Ki-67 (+ 80%), P53 (approximately 50%), CD43, and MPO was indicated.
Chemotherapy combined with radiochemotherapy.
A case of isolated myeloid sarcoma occurring simultaneously in the pancreas and orbit has never been reported.
Isolated myeloid sarcoma.
This case contributes to deepening our understanding of the diagnosis of isolated myeloid sarcoma. We should combine various laboratory test results, especially pathologic and immunohistochemical results, to assist in diagnosis. Surgery is not recommended for these cases, and minimally invasive methods are preferred for pathological examinations because surgery may delay treatment and affect the prognosis of patients. In addition, we should have a sense of differentiation for atypical cases, and the monism explanation should be considered first for multi-site lesions.