Published online Mar 16, 2022. doi: 10.12998/wjcc.v10.i8.2439
Peer-review started: December 1, 2021
First decision: December 27, 2021
Revised: January 12, 2022
Accepted: January 27, 2022
Article in press: January 27, 2022
Published online: March 16, 2022
Processing time: 99 Days and 16.2 Hours
Obstetric hemorrhage is the leading cause of maternal mortality globally, especially in China. The key to a successful rescue is immediate and rapid blood transfusion. Autotransfusion has become an integral part of clinical blood transfusion, with intraoperative cell salvage (IOCS) being the most widely used.
In this paper, the application of IOCS in cesarean section, monitoring of amniotic fluid embolization, and other related indications are discussed, demonstrating its safety in cesarean section.
This study aimed to investigate the application of IOCS in cesarean section.
A total of 87 patients who underwent cesarean section and blood transfusion in our hospital from March 2015 to June 2020 were enrolled in this prospective controlled study.
Before and after transfusion, no significant differences were observed in hemor-heology and the coagulation function indices between the two groups. About 24 h after transfusion, the erythrocyte count, platelet ratio, and fibrinogen value significantly decreased in the two groups; the PLT value significantly decreased in the two groups; the activated partial thromboplastin time, prothrombin time, and activated clotting time significantly increased in the two groups; and no statistical differences were observed in the hemorheology and coagulation function indices between the two groups. Furthermore, there was no significant difference in the incidence of adverse reactions between the two groups.
IOCS has a negligible effect on hemorheology and coagulation function in patients undergoing cesarean section and does not increase the risk of amniotic fluid embolism.
The principle of IOCS should be strictly followed during operation, which is worth promoting.