Wang M, Liu HF, Zhang YZZ, Zou ZQ, Wu ZQ. Hemolymphangioma with multiple hemangiomas in liver of elderly woman with history of gynecological malignancy: A case report. World J Clin Cases 2021; 9(32): 9948-9953 [PMID: 34877335 DOI: 10.12998/wjcc.v9.i32.9948]
Corresponding Author of This Article
Zhou-Quan Wu, PhD, Chief Doctor, Department of Anesthesiology, Changzhou Second People's Hospital Affiliated to Nanjing Medical University, No. 68 Gehu Middle Road, Wujin District, Changzhou 213003, Jiangsu Province, China. wuzhouquan2005@126.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Nov 16, 2021; 9(32): 9948-9953 Published online Nov 16, 2021. doi: 10.12998/wjcc.v9.i32.9948
Hemolymphangioma with multiple hemangiomas in liver of elderly woman with history of gynecological malignancy: A case report
Min Wang, Hai-Feng Liu, Yan-Zhen-Zi Zhang, Zhi-Qing Zou, Zhou-Quan Wu
Min Wang, Zhi-Qing Zou, Zhou-Quan Wu, Department of Anesthesiology, Changzhou Second People's Hospital Affiliated to Nanjing Medical University, Changzhou 213003, Jiangsu Province, China
Hai-Feng Liu, Department of Radiology, Third Affiliated Hospital of Soochow University and Changzhou First People's Hospital, Changzhou 213003, Jiangsu Province, China
Yan-Zhen-Zi Zhang, Department of Pathology, Third Affiliated Hospital of Soochow University and Changzhou First People’s Hospital, Changzhou 213003, Jiangsu Province, China
Author contributions: Wang M and Wu ZQ contributed to the design, analysis, and drafting of the manuscript; Wang M and Liu HF contributed to the analysis, and critically revised the manuscript; Zhang YZZ explained the microscopic and immumohistochemical staining; Wu ZQ and Zou ZQ critically revised the manuscript; and all authors read and approved the final manuscript.
Supported byThe Scientific Research Project of Jiangsu Provincial Health Commission, No. H2018047; Youth Project of Changzhou City Health Commission, No. QN202022; and Young Talent Development Plan of Changzhou Health Commission, No. CZQM202105.
Informed consent statement: Informed written consent was obtained from the patient and his parents for publication of this report and the accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: This study was conducted based on Care Checklist (2016) statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhou-Quan Wu, PhD, Chief Doctor, Department of Anesthesiology, Changzhou Second People's Hospital Affiliated to Nanjing Medical University, No. 68 Gehu Middle Road, Wujin District, Changzhou 213003, Jiangsu Province, China. wuzhouquan2005@126.com
Received: June 12, 2021 Peer-review started: June 12, 2021 First decision: June 25, 2021 Revised: July 2, 2021 Accepted: September 8, 2021 Article in press: September 8, 2021 Published online: November 16, 2021 Processing time: 150 Days and 10.1 Hours
Abstract
BACKGROUND
Hepatic hemolymphangioma is an extremely rare benign congenital malformation composed of cystically dilated lymphatic and blood vessels, and they have nonspecific clinical symptoms and laboratory results. In this study, hepatic hemolymphangioma with multiple hemangiomas in an elderly woman was initially reported and analyzed.
CASE SUMMARY
A 61-year-old female patient, with a history of hysterectomy and bilateral adnexectomy, was referred to the hepatobiliary surgery department with the complaint of multiple hepatic hemangiomas that had been diagnosed 2 years prior in a preoperative contrast-enhanced computed tomography (CECT) examination. Upon entering our hospital, no abnormal physical examination and laboratory data were found. The latest CECT revealed a new 7.0 cm × 6.2 cm cystic-solid lesion with multiple internal divisions in segment II of the liver, with delayed CECT enhancement characteristics that presented as solid parts with internal division. On the positron emission tomography (PET)/CT, no significant uptake of 18F-fluorodeoxyglucse was observed. Finally, hepatic hemolymphangioma was confirmed based on the pathological and immunohistochemical results after surgery. At 1-year follow-up, her posthepatectomy evaluation was uneventful, and she had recovered full activity. In addition, no postoperative recurrent or residual lesion was found on CECT imaging.
CONCLUSION
Hepatic hemolymphangioma with multiple hemangiomas was reported and observed by CECT and PET/CT imaging.
Core tip: To the best of our knowledge, this is the first report of hepatic hemolymphangioma with multiple hemangiomas and the associated features observed by contrast-enhanced computed tomography (CECT) and 18F-fluorodeoxyglucose positron emission tomography/computed tomography. In addition, this case was beneficial for confirming the pathogenesis of hepatic hemolymphangioma caused by surgery. Finally, posthepatectomy evaluation was uneventful, and no postoperative recurrent or residual lesion was found on CECT imaging, presenting a good prognosis.
