Advances in deep learning for computed tomography denoising

Abstract

Computed tomography (CT) has seen a rapid increase in use in recent years. Radiation from CT accounts for a significant proportion of total medical radiation. However, given the known harmful impact of radiation exposure to the human body, the excessive use of CT in medical environments raises concerns. Concerns over increasing CT use and its associated radiation burden have prompted efforts to reduce radiation dose during the procedure. Therefore, low-dose CT has attracted major attention in the radiology, since CT-associated x-ray radiation carries health risks for patients. The reduction of the CT radiation dose, however, compromises the signal-to-noise ratio, which affects image quality and diagnostic performance. Therefore, several denoising methods have been developed and applied to image processing technologies with the goal of reducing image noise. Recently, deep learning applications that improve image quality by reducing the noise and artifacts have become commercially available for diagnostic imaging. Deep learning image reconstruction shows great potential as an advanced reconstruction method to improve the quality of clinical CT images. These improvements can provide significant benefit to patients regardless of their disease, and further advances are expected in the near future.

Keywords: Denoising; Deep learning; Computer-assisted imaging processing; Iterative reconstruction; Radiation dose

Core Tip: Early application of deep learning techniques have shown success in the denoising of computed tomography (CT) images, especially low-dose CT images, and future advances are expected to provide additional benefit.