Copyright
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Blue LED as a new treatment to vaginal stenosis due pelvic radiotherapy: Two case reports
Daniela Barros, Cecília Alvares, Teresa Alencar, Priscila Baqueiro, Augusto Marianno, Rafael Alves, Juliana Lenzi, Laura Ferreira Rezende, Patricia Lordelo
Daniela Barros, Oncology Department, Hospital Santa Izabel, Salvador 40290-000, Brazil
Daniela Barros, Cecília Alvares, Teresa Alencar, Priscila Baqueiro, Augusto Marianno, Rafael Alves, Patricia Lordelo, Pelvic Floor Care Center (CAAP) and Postgraduate, Bahiana School of Medicine and Public Health, Salvador 40290-000, Brazil
Daniela Barros, Oncology Department, NOB/ Grupo Oncoclinicas, Salvador 40290-000, Brazil
Juliana Lenzi, Laura Ferreira Rezende, Pelvic Floor Care Center (CAAP), University Center of the Associated Teaching Faculties, Campinas 40000000, Brazil
Patricia Lordelo, Physiotherapy, Instituto Patrícia Lordelo - IPL, Salvador 40290-000, Brazil
Author contributions: Barros D, Alencar T, Alvares C and Lordelo P contributed equally to this work; Barros D, Alencar T, Alvares C and Lordelo P drafted the manuscript; Baqueiro P, Marianno A and Alves R contributed to data acquisition; Barros D, Alencar T, Alvares C, Lordelo P, Lenzi J and Rezende LF contributed to data analysis and interpretation; all authors have read and approve the final manuscript.
Informed consent statement: All study participants provided informed written consent prior to study enrollment. We will be in accordance with Good Clinical Practice Guidelines and Declaration of Helsinki.
Conflict-of-interest statement: Lordelo P: Since she was the developers of the LED equipment (patent number INPI: BR 10 2017 026980 9), used in the present study. It should be noted that the technology has already been transferred to the responsible industry. All other authors declare that there is no conflict.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
http://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Patricia Lordelo, PhD, Associate Professor, Physiotherapist, Postdoc, Pelvic Floor Care Center (CAAP) and Postgraduate, Bahiana School of Medicine and Public Health, Av Dom João VI, 256, Brotas, Salvador 40290-000, Brazil.
pvslordelo@hotmail.com
Received: February 22, 2021
Peer-review started: February 22, 2021
First decision: April 14, 2021
Revised: April 19, 2021
Accepted: July 13, 2021
Article in press: July 13, 2021
Published online: August 16, 2021
Processing time: 164 Days and 13.5 Hours
BACKGROUND
Currently, the advancement cancer treatment technology improves overall survival, however, adverse events are still a challenge for health professional. Genitourinary syndrome of menopause and vaginal stenosis are conditions that impact the quality of life of patients undergoing radiotherapy. We present two such cases in patients with previous cervical and endometrial cancer. These conditions were handled with an innovative method using an energy-based device with blue light emitting diode for concomitant vaginal and vulvar irradiation. Positive impact in clinical findings, cytologic changes, and referred symptoms were documented.
CASE SUMMARY
One patient diagnosed with vaginal severe vaginal stenosis with previous cervix cancer treatment and other patient diagnosed with mild stenosis with severe dyspareunia and recent endometrium cancer treatment were considered for vulvovaginal treatment with weekly blue led device and closely evaluated with repeated validated questionnaires and cytological samples.
CONCLUSION
This innovative technique showed an improvement in all areas of the examiner's criteria, the cytological criteria, and most bothered symptoms.
Core Tip: Vaginal stenosis brings a negative impact on patients' quality of life, with permanent discomfort for cancer survivors. Energy based devices have emerged as non-hormonal treatments for vaginal disease. We present two cases of an innovative technique to treat this post radiotherapy complication.
