Published online Jul 16, 2021. doi: 10.12998/wjcc.v9.i20.5605
Peer-review started: February 9, 2021
First decision: March 25, 2021
Revised: April 1, 2021
Accepted: May 15, 2021
Article in press: May 15, 2021
Published online: July 16, 2021
Processing time: 147 Days and 20 Hours
Superficial CD34-positive fibroblast tumors (SCPFTs) are newly recognized fibroblast and myofibroblast tumors representing intermediate tumors. To the best of our knowledge, fewer than 50 cases have been reported. Perianal SCPFT has not been previously reported.
A 55-year-old man was hospitalized upon discovering a painless perianal lump 10 d prior. Physical examination showed a lump of approximately 3 cm × 4 cm in the 7 to 8 o’clock direction in the perianal area. Perianal abscess was considered the primary diagnosis. Lump removal surgery was performed under epidural anesthesia. Postoperative pathology showed a well-circumscribed, soft tissue-derived, spindle-cell tumor with strong CD34 positivity by immunohistochemistry. The final diagnosis was perianal SCPFT. There were no complications, and the patient was followed for more than 8 mo without recurrence or metastasis.
We report a case of perianal superficial CD34-positive fibroblast tumor. This rare mesenchymal neoplasm has distinctive histomorphology, which is important for diagnosis. Comprehensive consideration of clinical information, imaging, histology, and immunohistochemistry is important for diagnosis.
Core Tip: We present a new case of perianal superficial CD34-positive fibroblast tumor. Surgery is the main treatment for superficial painless slowly growing masses. Postoperative immunohistochemical examination showed that strong positivity for CD34 and good prognosis were the characteristics of the case.