Published online Jun 6, 2021. doi: 10.12998/wjcc.v9.i16.3951
Peer-review started: November 22, 2020
First decision: December 24, 2020
Revised: January 2, 2021
Accepted: March 5, 2021
Article in press: March 5, 2021
Published online: June 6, 2021
Processing time: 160 Days and 19 Hours
Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disease that affects the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobulin G).
We report the case of a 45-year-old woman with a history of Sjogren's syndrome who was diagnosed with NMOSD accompanied by spinal cord injury and left calf intermuscular vein thrombosis. The patient received hormone shock and gamma globulin therapy in the acute phase and standard rehabilitation treatment during convalescence. Upon discharge, the patient was able to control urination and defecation, stand independently, and walk short distances with the aid of a walker.
This case suggests that pharmacotherapy and standard rehabilitation treatment can improve the prognosis of NMSOD patients.
Core Tip: Neuromyelitis optica spectrum disorder (NMOSD) is a demyelinating autoimmune disorder of the central nervous system. It typically manifests as optic neuritis or extensive longitudinal myelitis, with or without the presence of anti-aquaporin protein 4 autoantibodies (immunoglobulin G). We report the case of a 45-year-old woman with a history of Sjogren's syndrome who was diagnosed with NMOSD accompanied by spinal cord injury and left calf intermuscular vein thrombosis. The patient received hormone shock and gamma globulin therapy in the acute phase and standard rehabilitation treatment during convalescence.