Published online Jan 6, 2021. doi: 10.12998/wjcc.v9.i1.211
Peer-review started: July 15, 2020
First decision: August 8, 2020
Revised: August 17, 2020
Accepted: November 12, 2020
Article in press: November 12, 2020
Published online: January 6, 2021
Processing time: 170 Days and 4.1 Hours
Sclerosing angiomatoid nodular transformation (SANT) is a rare disease of the spleen. It has unique pathological features and mimics splenic tumor on radiological imaging.
A 47-year-old woman was incidentally found to have a splenic mass on abdominal ultrasound. She had a 10-cm postoperative scar in the lower abdomen due to previous cesarean sections. The patient had a past history of anemia of unknown etiology for 20 years. The patient underwent laparoscopic splenectomy. The postoperative course was uneventful, with a hospital stay of 7 d. The histopathological examination of the spleen revealed SANT. At the 6-mo follow-up, the patient remained disease-free.
SANT is a rare benign disease mimicking a malignant tumor. A definitive diagnosis can be made only on histopathology.
Core Tip: We report the case of a 47-year-old lady with long-standing anemia with an incidentally detected splenic mass of 5.9 cm × 5.1 cm that appeared malignant on computed tomography. The patient underwent laparoscopic splenectomy. Histopathological examination of the spleen revealed sclerosing angiomatoid nodular transformation (SANT). SANT is a rare benign disease of the spleen that mimics malignancy on radiological imaging. Preoperative diagnosis of SANT is difficult. SANT should be included in the differential diagnosis when treating patients with a splenic mass.