Published online Nov 6, 2020. doi: 10.12998/wjcc.v8.i21.5426
Peer-review started: April 15, 2020
First decision: April 24, 2020
Revised: September 8, 2020
Accepted: September 16, 2020
Article in press: September 16, 2020
Published online: November 6, 2020
Processing time: 204 Days and 17 Hours
There is a common pathologic relationship between parathyroid adenoma and thyroid cancer, but this relationship is infrequent in pregnant patients with primary hyperparathyroidism (PHPT).
A 27-year-old gravida 1 woman was transferred to our hospital at 16 wk of pregnancy. She was diagnosed with parathyroidoma, papillary carcinoma of the thyroid and thyroid adenoma and was managed surgically. Both the mother and the newborn were stable after a right inferior parathyroidectomy and total thyroidectomy. The healthy infant was delivered at the 40th week of pregnancy. The mother had no evidence of recurrence over three years of follow-up.
Awareness of concomitant PHPT and thyroid diseases may help in managing patients with a history of hypercalcemia.
Core Tip: Primary hyperparathyroidism (PHPT) with parathyroid adenoma associated with papillary cancer and adenoma of the thyroid is unusual. The preliminary test results showed severe hypercalcemia. The level of parathyroid hormone found in further laboratory tests was elevated and a diagnosis of PHPT was determined. Right lower parathyroid gland and total thyroidectomy were performed. This clinical case illustrates the need for awareness of concomitant PHPT and thyroid diseases.