Retrospective Study
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Oct 26, 2020; 8(20): 4735-4742
Published online Oct 26, 2020. doi: 10.12998/wjcc.v8.i20.4735
Sleep quality of patients with postoperative glioma at home
Yang Huang, Zi-Juan Jiang, Juan Deng, Yu-Juan Qi
Yang Huang, Zi-Juan Jiang, Juan Deng, Yu-Juan Qi, Department of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Author contributions: Huang Y and Jiang ZJ designed the research; Huang Y, Jiang ZJ, and Deng J performed the research; Huang Y and Qi YJ analyzed the data; Jiang ZJ and Deng J wrote the paper; Huang Y and Deng J revised the manuscript.
Supported by Nanjing Medical Science and Technique Development Foundation, No. QRX17087.
Institutional review board statement: The study was performed in accordance with the Helsinki Declaration, and the protocol and informed consent form used were approved beforehand by the Institutional Review Board of Nanjing Brain Hospital (IRB No. 2020-KY091-01).
Informed consent statement: Written informed consent was waived by the IRB.
Conflict-of-interest statement: The authors declare no conflicts of interest regarding this manuscript.
Data sharing statement: There are no additional data available for this study.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zi-Juan Jiang, MM, Associate Professor, Department of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, No. 264 Guangzhou Road, Nanjing 210029, Jiangsu Province, China. jiangzi_j@163.com
Received: May 9, 2020
Peer-review started: May 9, 2020
First decision: June 7, 2020
Revised: June 19, 2020
Accepted: September 9, 2020
Article in press: September 9, 2020
Published online: October 26, 2020
Processing time: 170 Days and 3.5 Hours
Abstract
BACKGROUND

The sleep quality of patients with postoperative glioma at home has not been reported worldwide. In this study, the sleep quality of postoperative glioma patients at home was explored through telephone interviews.

AIM

To investigate the sleep quality of patients with postoperative glioma.

METHODS

Glioma patients who were treated and operated on at Nanjing Brain Hospital from May 2012 to August 2019 were selected as participants via convenience sampling. A total of 549 patients were recruited by telephone, and 358 of those patients responded to the Pittsburgh Sleep Quality Index (PSQI).

RESULTS

The total PSQI score was 5.19 ± 3.39 in all patients with postoperative glioma, which was higher than that of the normal group. There were 135 patients with poor sleep quality (PSQI > 7), which accounted for 37.7% of all respondents. The scores of the seven dimensions of the PSQI were sleep latency (1.22 ± 1.05), sleep disturbance (1.12 ± 0.98), subjective sleep quality (1.03 ± 0.92), habitual sleep efficiency (1.02 ± 0.91), daytime dysfunction (0.95 ± 0.43), sleep persistence (0.83 ± 0.76), and use of sleeping medication (0.25 ± 0.24). The results showed that the subjective sleep quality of the patients who underwent an operation 1-2 years ago was worse than that of the patients who underwent an operation more than 2 years ago (P < 0.05). Older patients had worse sleep latency and sleep duration scores than younger patients (P < 0.05). Sleep disturbance and daytime dysfunction were worse in patients who received postoperative radiotherapy/ chemotherapy (P < 0.05).

CONCLUSION

The sleep quality of patients with postoperative glioma at home is worse than that of normal adults. Moreover, difficulty falling asleep and sleep disorders are common complications among these patients, and age, postoperative duration, and postoperative chemoradiotherapy could affect sleep quality.

Keywords: Sleep quality; Postoperative; Glioma patients; Radiotherapy; Chemotherapy; Outcome

Core Tip: This study showed that patients with postoperative glioma had relatively good sleep quality 1-2 years after being discharged from the hospital. After 2 years, patients began to worry about recurrence, and this worry was accompanied by anxiety and pain, which often led to sleep disorders. Moreover, our study showed that older patients are less likely than younger patients to sleep longer and to sleep more efficiently. Thus, sleep disturbance was an important factor affecting the outcomes and quality of life of patients. Sufficient attention should be paid to these patients.