Liu J, Wu XW, Hao XW, Duan YH, Wu LL, Zhao J, Zhou XJ, Zhu CZ, Wei B, Dong Q. Spontaneous regression of stage III neuroblastoma: A case report. World J Clin Cases 2020; 8(2): 436-443 [PMID: 32047796 DOI: 10.12998/wjcc.v8.i2.436]
Corresponding Author of This Article
Qian Dong, MD, Professor, Department of Pediatric Surgery, Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Shinan District, Qingdao 266000, Shandong Province, China. dongqianyz1@163.com
Research Domain of This Article
Pediatrics
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Jan 26, 2020; 8(2): 436-443 Published online Jan 26, 2020. doi: 10.12998/wjcc.v8.i2.436
Spontaneous regression of stage III neuroblastoma: A case report
Jie Liu, Xiong-Wei Wu, Xi-Wei Hao, Yu-He Duan, Ling-Ling Wu, Jing Zhao, Xian-Jun Zhou, Cheng-Zhan Zhu, Bin Wei, Qian Dong
Jie Liu, Xiong-Wei Wu, Xi-Wei Hao, Yu-He Duan, Ling-Ling Wu, Jing Zhao, Xian-Jun Zhou, Qian Dong, Department of Pediatric Surgery, Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China
Jie Liu, Department of Pediatric Surgery, Yijishan Hospital of Wannan Medical College, Wuhu 241000, Anhui Province, China
Cheng-Zhan Zhu, Bin Wei, Shandong Key Laboratory of Digital Medicine and Computer Assisted Surgery, Qingdao 266000, Shandong Province, China
Author contributions: Liu J and Dong Q designed the research; Wu XW and Hao XW obtained the clinical data and measured the radiological parameters; Duan YH and Wu LL were responsible for the staining of pathological sections; Zhao J and Zhou XJ performed the three-dimensional image reconstruction; Zhu CZ and Wei B prepared the tables and figures; Liu J prepared the manuscript; Dong Q revised the manuscript.
Supported byQingdao Civic Science and Technology Program, No. 17-3-3-8-nsh.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Qian Dong, MD, Professor, Department of Pediatric Surgery, Affiliated Hospital of Qingdao University, No. 16, Jiangsu Road, Shinan District, Qingdao 266000, Shandong Province, China. dongqianyz1@163.com
Received: November 4, 2019 Peer-review started: November 4, 2019 First decision: December 4, 2019 Revised: December 5, 2019 Accepted: December 22, 2019 Article in press: December 22, 2019 Published online: January 26, 2020 Processing time: 74 Days and 1.6 Hours
Abstract
BACKGROUND
Neuroblastoma (NB) is the most common type of extracranial solid tumour in children. The overall prognosis of NB is poor, but at the same time, NB shows significant clinical diversity. NB can demonstrate spontaneous regression or can differentiate into benign ganglioneuroma.
CASE SUMMARY
This study retrospectively analyzed the clinical data of a patient with spontaneous regression of stage III NB who was admitted in May 2015. Studies of the spontaneous regression of NB published from October 1946 to September 2019 were retrieved through PubMed. The clinical manifestations, diagnosis, treatment, and follow-up results were analysed.
CONCLUSION
Spontaneous regression of stage III NB is rare in the clinic. The report of this case is an important supplement to the study of the spontaneous regression of NB.
Core tip: Neuroblastoma (NB) is the most common type of extracranial solid tumour in children. The overall prognosis of NB is poor, but at the same time, NB shows significant clinical diversity. NB can demonstrate spontaneous regression or can differentiate into benign ganglioneuroma. This study retrospectively analyzed the clinical data of a patient with spontaneous regression of stage III NB who was admitted in May 2015. Studies of the spontaneous regression of NB published from October 1946 to September 2019 were retrieved through PubMed. The clinical manifestations, diagnosis, treatment, and follow-up results were analysed. Spontaneous regression of stage III NB is rare in the clinic. The report of this case is an important supplement to the study of the spontaneous regression of NB.
