Published online Aug 6, 2020. doi: 10.12998/wjcc.v8.i15.3164
Peer-review started: March 26, 2020
First decision: May 29, 2020
Revised: June 11, 2020
Accepted: July 14, 2020
Article in press: July 14, 2020
Published online: August 6, 2020
Processing time: 133 Days and 3.2 Hours
Traditional magnetic resonance (MR) diffusion-weighted imaging (DWI) uses a single exponential model to obtain the apparent diffusion coefficient to quantitatively reflect the diffusion motion of water molecules in living tissues, but it is affected by blood perfusion. Intravoxel incoherent motion (IVIM)-DWI utilizes a double-exponential model to obtain information on pure water molecule diffusion and microcirculatory perfusion-related diffusion, which compensates for the insufficiency of traditional DWI. In recent years, research on the application of IVIM-DWI in the diagnosis and treatment of hepatic diseases has gradually increased and has achieved considerable progress. This study mainly reviews the basic principles of IVIM-DWI and related research progress in the diagnosis and treatment of hepatic diseases.
Core tip: Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) utilizes a double-exponential model to obtain information on pure water molecule diffusion and microcirculatory perfusion-related diffusion, which makes up for the insufficiency of traditional DWI. In recent years, research on the application of IVIM-DWI in the diagnosis and treatment of hepatic diseases has gradually increased and has made great progress. This study mainly reviews the basic principles of IVIM-DWI and its research progress in the diagnosis and treatment of hepatic diseases.
