Cai JB, Wang JH, He M, Wang FL, Xiong JN, Mao JQ, Li MJ, Zhu K, Liang JW. Unusual presentation of bladder neuroblastoma in a child: A case report. World J Clin Cases 2020; 8(1): 194-199 [PMID: 31970187 DOI: 10.12998/wjcc.v8.i1.194]
Corresponding Author of This Article
Jin-Hu Wang, MD, Associate Professor, Surgical Oncologist, Division of Surgical Oncology, Department of Pediatric Surgery, Children’s Hospital, Zhejiang University School of Medicine;National Clinical Research Center for Child Health, No. 3333 Binsheng Road, Binjiang Distrcict, Hangzhou 310053, Zhejiang Province, China. wjh@zju.edu.cn
Research Domain of This Article
Pediatrics
Article-Type of This Article
Case Report
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Cai JB, Wang JH, He M, Wang FL, Xiong JN, Mao JQ, Li MJ, Zhu K, Liang JW. Unusual presentation of bladder neuroblastoma in a child: A case report. World J Clin Cases 2020; 8(1): 194-199 [PMID: 31970187 DOI: 10.12998/wjcc.v8.i1.194]
World J Clin Cases. Jan 6, 2020; 8(1): 194-199 Published online Jan 6, 2020. doi: 10.12998/wjcc.v8.i1.194
Unusual presentation of bladder neuroblastoma in a child: A case report
Jia-Bin Cai, Jin-Hu Wang, Min He, Fa-Liang Wang, Jie-Ni Xiong, Jun-Qing Mao, Min-Ju Li, Kun Zhu, Jia-Wei Liang
Jia-Bin Cai, Jin-Hu Wang, Min He, Fa-Liang Wang, Jie-Ni Xiong, Jun-Qing Mao, Min-Ju Li, Division of Surgical Oncology, Department of Pediatric Surgery, Children’s Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China
Kun Zhu, Department of Pathology, Children’s Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China
Jia-Wei Liang, Department of Radiology, Children’s Hospital, Zhejiang University School of Medicine, ; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China
Author contributions: All authors contributed equally to this work; Liang JW collected the image data; Cai JB contributed to manuscript drafting and reviewed the literature; Zhu K performed the pathological interpretation; Mao JQ and Li MJ were the oncologists who treated the patient; Xiong JN collected and the patient’s information in detail; Wang JH, Cai JB, He M, Wang FL were the surgeons who treated the patient; Wang JH was the supervisor who monitored treatment of the patient; all authors issued final approval for the version to submitted.
Supported byScience Technology Research Program of Zhejiang Province, No. 2017C33047; Scientific research project of Zhejiang education department, No. N20140124); Medical Health Science and Technology Project of Zhejiang Provincial Health Commission, No. 2019KY093.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Jin-Hu Wang, MD, Associate Professor, Surgical Oncologist, Division of Surgical Oncology, Department of Pediatric Surgery, Children’s Hospital, Zhejiang University School of Medicine;National Clinical Research Center for Child Health, No. 3333 Binsheng Road, Binjiang Distrcict, Hangzhou 310053, Zhejiang Province, China. wjh@zju.edu.cn
Received: October 26, 2019 Peer-review started: October 26, 2019 First decision: November 21, 2018 Revised: November 30, 2019 Accepted: December 13, 2019 Article in press: December 13, 2019 Published online: January 6, 2020 Processing time: 72 Days and 12.1 Hours
Abstract
BACKGROUND
Neuroblastoma is an extracranial malignant tumor in children that is most often located in the adrenal gland and sympathetic ganglion. Here, we present a rare case of neuroblastoma originating from the urinary bladder.
CASE SUMMARY
A 3-year-old girl presented with lower abdominal pain with micturition. Ultrasound revealed a lower abdominal mass. Abdominal computed tomography scan displayed a solitary mass at the top of the urinary bladder. Blood levels of neuron-specific enolase and lactate dehydrogenase were elevated. We treated the child with partial cystectomy and six courses of chemotherapy, and the outcome at 4-year follow-up was unremarkable.
CONCLUSION
Neuroblastoma should be considered when tumors are located in the urinary bladder, especially in the dome; although this presentation is rare, the prognosis is very good.
Core tip: Rhabdomyosarcoma is a common bladder malignancy in children. We here report a rare case of bladder neuroblastoma in a child. The patient was treated with a standard strategy and had a good outcome. Our findings suggest that children with neuroblastoma have good prognosis.
