An JK, Woo JJ, Hong YO. Malignant sweat gland tumor of breast arising in pre-existing benign tumor: A case report. World J Clin Cases 2019; 7(19): 3033-3038 [PMID: 31624751 DOI: 10.12998/wjcc.v7.i19.3033]
Corresponding Author of This Article
Jin Kyung An, MD, PhD, Associate Professor, Department of Radiology, Nowon Eulji Medical Center, 68 Hangeulbiseok-Ro, Nowon-Gu, Seoul 01830, South Korea. jkan0831@eulji.ac.kr
Research Domain of This Article
Medicine, Research & Experimental
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Oct 6, 2019; 7(19): 3033-3038 Published online Oct 6, 2019. doi: 10.12998/wjcc.v7.i19.3033
Malignant sweat gland tumor of breast arising in pre-existing benign tumor: A case report
Jin Kyung An, Jeong Joo Woo, Young Ok Hong
Jin Kyung An, Jeong Joo Woo, Department of Radiology, Nowon Eulji Medical Center, Eulji University, Seoul 01830, South Korea
Young Ok Hong, Department of Pathology, Nowon Eulji Medical Center, Eulji University, Seoul 01830, South Korea
Author contributions: An JK reviewed the ultrasound and MR images and contributed to original draft preparation, review, and editing. Woo JJ reviewed the ultrasound and MR images and contributed to original draft review and editing. Hong YO was reviewed the pathology and prepared the pathology photographs and description.
Informed consent statement: This study was reviewed and approved as a retrospective case report by the Institutional Review Board of Eulji Medical Center, Seoul, Korea (EMCIRB 19-47), with informed consent from the patient waived.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Jin Kyung An, MD, PhD, Associate Professor, Department of Radiology, Nowon Eulji Medical Center, 68 Hangeulbiseok-Ro, Nowon-Gu, Seoul 01830, South Korea. jkan0831@eulji.ac.kr
Telephone: +82-2-9708290 Fax: +82-2-9708346
Received: May 28, 2019 Peer-review started: June 3, 2019 First decision: August 1, 2019 Revised: August 22, 2019 Accepted: September 9, 2019 Article in press: September 9, 2019 Published online: October 6, 2019 Processing time: 125 Days and 3.4 Hours
Abstract
BACKGROUND
Sweat glands belong to skin appendages. Sweat gland tumors are uncommon, especially when they occur as malignant tumors in the breast. We report a case of malignant sweat gland tumor of the breast, including imaging and pathological findings.
CASE SUMMARY
A 47-year-old woman visited our hospital with a non-tender palpable lesion in her left breast. The lesion had not shown changes for 10 years. However, it recently increased in size. Sonography showed a well circumscribed cystic lesion with internal debris and fluid-fluid level. Magnetic resonance imaging showed a well circumscribed oval mass with T1 hyper-intensity compared to muscle and T2 high signal intensity. There was a small enhancing mural component in the inner wall of the mass. The tumor was resected. Its pathologic result was a malignant transformation of benign sweat gland tumor such as hidradenoma. The lesion was treated with excision and radiation therapy. At 1-year follow up, there was no local recurrence or metastasis in the patient.
CONCLUSION
In the case of a rapid growing cystic mass in the nipple and subareola, it is necessary to distinguish it from a malignant sweat gland tumor.
Core tip: Sweat gland tumors of the breast are rare. They are clinically similar to benign cutaneous lesions. Imaging findings of sweat gland tumors have been rarely reported. This case will help us understand types of sweat gland tumors, the distinction between cutaneous and breast parenchymal lesions, and differential diagnosis of cutaneous lesions.
