Case Report
Copyright ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Clin Cases. Jul 26, 2019; 7(14): 1876-1883
Published online Jul 26, 2019. doi: 10.12998/wjcc.v7.i14.1876
Noteworthy effects of a long-pulse Alexandrite laser for treatment of high-risk infantile hemangioma: A case report and literature review
Wen-Ting Su, Ji-Xin Xue, You-Hui Ke
Wen-Ting Su, You-Hui Ke, Medical Cosmetology Department, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Wenzhou Skin Disease and Plastic Surgery Hospital, Wenzhou 325000, Zhejiang Province, China
Ji-Xin Xue, Department of Hand and Plastic Surgery, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China
Author contributions: Ke YH and Su WT planned the study, oversaw the study data collection and analysis, and wrote the manuscript; Xue JX provided input into the data collection and analysis and helped write the manuscript; Su WT, Ke YH, and Xue JX modified and edited the manuscript; all authors approved the final manuscript.
Supported by Zhejiang Provincial Natural Science Foundation of China, No. LQ16H110001 and No. LQ13C100001; Wenzhou Science and Technology Bureau Foundation, No. 2017Y0750; and Medicine and Health Science and Technology Projects of Zhejiang Province of China, No. 2013KYA128.
Informed consent statement: Consent was obtained from relatives of the patient for publication of this report and the accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: You-Hui Ke, MD, Doctor, Department of Dermatology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, No. 75, Jinxiu Road, Wenzhou 325000, Zhejiang Province, China. 672673450@qq.com
Telephone: +86-13867776098 Fax: +86-577-88915775
Received: February 14, 2019
Peer-review started: February 15, 2019
First decision: March 14, 2019
Revised: May 3, 2019
Accepted: May 23, 2019
Article in press: May 23, 2019
Published online: July 26, 2019
Processing time: 162 Days and 20.7 Hours
Abstract
BACKGROUND

We have previously proved that treatment of thick/deep infantile hemangiomas (IHs) with a long-pulse Alexandrite laser was clinically effective and safe. This article aims to investigate the efficiency of long-pulse Alexandrite laser use in treating thick and high-risk IHs located in particular anatomic areas and provides some new data on this issue.

CASE SUMMARY

A two-month-old girl with a thick and high-risk IH covering most of the right labia majora was examined in this study. The infant received four treatment sessions at 4- to 6-wk intervals with a long-pulse Alexandrite laser with settings as follows: 3 ms pulse duration, 8 mm spot size, 45 to 50 J/cm2 fluences, and dynamic cooling device (DCD) spray duration of 90 ms with a delay of 80 ms. Following each of the four treatment sessions, the IH showed a remarkable reduction in thickness and size without any sign of relapse. Ten months after the last treatment, the IH had completely regressed without adverse effects. During the laser treatment, no severe side effects were observed; blistering occurred only immediately after treatment and then scabbed over the next day, gradually improving in the following days.

CONCLUSION

Long-pulse Alexandrite laser treatment may be considered one of the first-line noninvasive therapeutic options for the treatment of thick IH.

Keywords: Alexandrite laser; Infantile hemangiomas; Treatment; Case report

Core tip: Infantile hemangiomas (IHs) are the most common benign tumors of infancy. In this paper, we describe a two-month-old female who presented with a thick IH covering most of the right labia majora and was treated using a long-pulse Alexandrite laser, and we review the literature to further understand IH, including its definition, diagnosis, and treatment.