Published online Jan 16, 2016. doi: 10.12998/wjcc.v4.i1.30
Peer-review started: May 8, 2015
First decision: July 26, 2015
Revised: August 26, 2015
Accepted: November 3, 2015
Article in press: November 4, 2015
Published online: January 16, 2016
Processing time: 253 Days and 8.3 Hours
We would like offering our experience about a very rare and underestimated type of gastrointestinal lipoma, which is the lipoma with precancerous or frankly malignant features of the mucosal epithelium, the so-called atypical lipoma. So far, only few cases have been described in the world literature. Recently, we grappled with what we think the first case of atypical colonic lipoma presenting with adenocarcinomatous transformation of the overlying epithelium, as discussed in more detail below. We propose a new definition and classification for this kind of lesions and discuss about their diagnosis, treatment and prognosis.
Core tip: We report a case of atypical lipoma of the colon with malignant transformation of the mucosal epithelium. No standardized treatment exists. Endoscopic resection with close follow-up is probably the most appropriate management to pursue for this kind of lesions.