Wang XJ. Traditional Chinese medicine treatment of insomnia based on microbial-gut-brain axis theory. World J Clin Cases 2024; 12(36): 6867-6870 [PMID: 39726932 DOI: 10.12998/wjcc.v12.i36.6867]
Corresponding Author of This Article
Xue-Jian Wang, MD, PhD, Surgeon, Department of Neurosurgery, The Second Affiliated Hospital of Nantong University, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com
Research Domain of This Article
Neurosciences
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Clin Cases. Dec 26, 2024; 12(36): 6867-6870 Published online Dec 26, 2024. doi: 10.12998/wjcc.v12.i36.6867
Traditional Chinese medicine treatment of insomnia based on microbial-gut-brain axis theory
Xue-Jian Wang
Xue-Jian Wang, Department of Neurosurgery, The Second Affiliated Hospital of Nantong University, Nantong 226000, Jiangsu Province, China
Xue-Jian Wang, Department of Neurosurgery, Lueyang People's Hospital, Hanzhong 723000, Shaanxi Province, China
Author contributions: Wang XJ designed the research, drafted and revised the article; the author read and approved the final version of the manuscript to be published.
Supported byThe Science and Technology Program of Nantong Health Committee, China, No. MA2019003 and No. MA2021017; and The Science and Technology Program of Nantong City, China, No. KD2021JYYJYB025, No. JCZ2022040, and No. KD2022KYJJZD022.
Conflict-of-interest statement: The authors have no any conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xue-Jian Wang, MD, PhD, Surgeon, Department of Neurosurgery, The Second Affiliated Hospital of Nantong University, No. 666 Shengli Road, Chongchuan District, Nantong 226000, Jiangsu Province, China. 6841441@163.com
Received: May 28, 2024 Revised: September 6, 2024 Accepted: September 13, 2024 Published online: December 26, 2024 Processing time: 155 Days and 17.3 Hours
Abstract
In recent years, insomnia has gradually become a common disease in society, which seriously affects people's quality of life. At present, with the deepening of research on intestinal microbiota-gut-brain axis in Western medicine, many studies suggest that regulating the gastrointestinal tract can treat brain-related diseases. It is found that brain-gut-bacteria axis plays an important role in the prevention and treatment of primary insomnia. At present, although the clinical treatment of insomnia with Western medicine can improve the insomnia symptoms of patients to a certain extent, there are still obvious adverse reactions, such as anxiety and depression, drug addiction, etc., so long-term oral drug therapy cannot be carried out. Traditional Chinese medicine (TCM) and acupuncture techniques have certain therapeutic effects on insomnia. TCM believes that the brain and gastrointestinal system are connected through the meridian, and the pathophysiology is closely related. This paper will discuss the theory and feasibility of TCM for the treatment of insomnia from the pathological relationship between brain-gut axis, intestinal flora and insomnia.
Core Tip: In recent years, insomnia has gradually become a common disease in society, which seriously affects people's quality of life. At present, with the deepening of research on intestinal microbiota-gut-brain axis in Western medicine, many studies suggest that regulating the gastrointestinal tract can treat brain-related diseases.
